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concentration of 2% to 2.5%. Soda, juice, popsicles, and soups are inappropriate
rehydration solutions in dehydrated infants and children and should be
discouraged as they do not have the appropriate glucose-to-sodium ratio and are
not absorbed as easily as electrolyte solutions. Studies have evaluated half
strength apple juice (mixed with water) as an alternate therapy as compared to
ORT and have found fewer treatment failures most likely secondary to patient
taste preference. In developing countries, the addition of zinc supplementation in
patients older than 6 months of age with diarrhea has been shown to have
improved outcomes however current evidence does not show a benefit in wellnourished children in settings with low prevalence of zinc deficiency.
TABLE 22.4
ONDANSETRON DOSING FOR GASTROENTERITIS
Patient weight
(kg)
Dose
8–15
>15–30
>30
2-mg orally disintegrating tablet (½ tablet)
4-mg orally disintegrating tablet
8-mg orally disintegrating tablet
The amount of fluid to be administered is dependent on the degree of
dehydration. Mild dehydration reflects up to 5% weight loss, so 5% of the child’s
body weight (50 mL/kg) should be administered as small-volume frequent feeds.
Moderate dehydration represents up to 10% weight loss, so 10% of the child’s
weight (100 mL/kg) should be administered. An easy rule of thumb to remember
is that a mildly dehydrated patient can receive 1 mL/kg every 5 minutes and a
moderately dehydrated patient can receive 2 mL/kg every 5 minutes. As the child