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lymphadenopathy and splenomegaly. Finally HIV infection causes adenopathy in the
cervical, axillary, and inguinal regions, particularly during the acute phase of infection.
Nodes generally decrease in size after the first 1 to 2 weeks as the immune response to
infection subsides, however a modest degree of adenopathy can persist. Children with
unexplained recurrent or opportunistic infections, fevers, failure to thrive,
hepatosplenomegaly, and generalized adenopathy should be evaluated for HIV infection.