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Pediatric emergency medicine trisk 3040 3040

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Perform an electrocardiogram (EKG) in all seriously ill patients in whom
poisoning is being considered. Detectable conduction delays (prolongation of the
PR, QRS, and/or QT intervals) may provide diagnostic direction and impact
management by predicting imminent life-threatening cardiac rhythm
disturbances.
TABLE 102.7
FREQUENTLY USEFUL QUANTITATIVE TOXICOLOGY TESTS IN
PEDIATRIC PATIENTS
Drug/toxin

Optimal time after ingestion (hours)

Acetaminophen
Carbamazepine
Carboxyhemoglobin
Digoxin
Ethanol
Ethylene glycol
Iron
Lithium
Methanol
Methemoglobin
Phenobarbital
Phenytoin
Salicylate
Theophylline
Valproate

4
2–4
Immediate


4–6
½–1
½–1
4
2–4 a
½–1
Immediate
1–2
1–2
2–4 a
1–2 a
2–4

a Repeat

levels over 6 to 12 hours may be necessary with sustained-release preparations.
Adapted from Weisman RS, Howland MA, Flomenbaum NE. The toxicology laboratory. In: Goldfrank LR,
Flomenbaum NE, Lewin NA, et al., eds. Goldfrank’s Toxicologic Emergencies . 4th ed. Norwalk, CT:
Appleton & Lange; 1990.



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