Genetic analysis, structural modeling, and direct coupling analysis suggest a mechanism for phosphate signaling in Escherichia coli

ibutions
SGG planned, performed experiments, prepared, and edited the manuscript.
JM performed DCA, helped with analysis of data, and aided in preparing the
manuscript. TD, TR, and ME helped in the scanning mutagenesis. PR helped
with bioinformatic experimental planning and analysis. WRM designed
experiments, conducted experiments, aided in data analysis, and aided in
preparing and editing the manuscript.
Acknowledgements
We thank Kathryn Hanks, Alex Cummock, Evan Christensen, Bethany Evans,
Gregory Bowden, and Michael Barrus for help with sequence collection and
mutant characterization. This work was supported by Public Health Service
grant R15GM96222 from the National Institute of General Medical Sciences.
Declarations
The publication costs for this article were funded by the Department of
Microbiology and Molecular Biology at Brigham Young University, the
College of Life Sciences at Brigham Young University, and the Public Health
Service grant R15GM96222 from the National Institute of General Medical
Sciences.


Gardner et al. BMC Genetics 2015, 16(Suppl 2):S2
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19.

Authors’ details
Microbiology and Molecular Biology Department, Brigham Young University,
Provo, UT, USA. 2Department of Biology, Brigham Young University, Provo,
UT, USA.

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Published: 23 April 2015

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doi:10.1186/1471-2156-16-S2-S2
Cite this article as: Gardner et al.: Genetic analysis, structural modeling,
and direct coupling analysis suggest a mechanism for phosphate
signaling in Escherichia coli. BMC Genetics 2015 16(Suppl 2):S2.