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Công nghệ lên men Evaporation crystallization

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Y o u r P a r t n e r i n P e r f o r m a n c e
Y o u r P a r t n e r i n P e r f o r m a n c e
www.novasep.com
NVS - 57 - 2.3.P10.v1
03/07 -
INDUSTRIAL BIOTECH
Applexion® Evaporation and
Crystallization Solutions
Contacts
Technology
EUROPE
Michel COTILLON
264, avenue de la Mauldre
78680 Epone - FRANCE
Phone: +33 (0)1 30 90 50 00
Fax: +33 (0)1 30 91 05 31

ASIA - Novasep ASIA
Jean de LATAILLADE
Build No.1 #306-308,
Lane 898, Hailei Road,
Zhangjiang Hi-Tech Park,
Shanghai 201203 - CHINA
Phone: +86 (0)21 5407 0208
Fax: +86 (0)21 5407 0206

USA - Novasep, Inc.
23, Creek Circle
Boothwyn, PA 19061 - USA
Phone: +1 610 494 0447
Fax: +1 610 494 1988



Latin America
Patrick PRINTEMPS
Phone: +33 (0)1 30 90 50 00
Fax: +33 (0)1 30 91 05 31

East-Middle East
Dominique PAILLAT
Phone: +33 (0)1 30 90 50 00
Fax: +33 (0)1 30 91 05 31

© Novasep 2007.1
Copyright and Trademark Information:
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on this brochure are the property of Group Novasep SAS and/or
its a liates. No right or license is granted to any other party. Any
unauthorized use without the express prior written consent of
Groupe Novasep is prohibited.
Disclaimers:
The information contained on this brochure are provided “as is”,
for informational purposes only, without any representation or
warranty of accuracy or completeness. In no event will Groupe
Novasep be liable to any party for any damages or any other
losses for access or reliance upon any information contained on
this brochure.
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Applexion
(St Maurice de B.)
Applexion
(St Maurice de B.)
Novasep
Partner
(Mumbai)
Novasep
Partner
(Mumbai)
Novasep Asia
(Shanghai)
Novasep Asia
(Shanghai)
Novasep, Inc.
(Boothwyn)
Novasep, Inc.
(Boothwyn)
Applexion
(Epone)
Applexion
(Epone)
Novasep
Germany

(Frankfurt)
Novasep
Germany
(Frankfurt)
Novasep SAS
Groupe Novasep
(Pompey)
Novasep SAS
Groupe Novasep
(Pompey)
In your opinion,
is performance
a matter of :
C o s t ?
R e c i p e ?
A d d e d - V a l u e ?
O t h e r ?
Applications using Applexion®
Evaporation and Crystallization
Solutions
Cost
To meet your cost objectives, we deve-
lop and implement crystallization and
evaporation processes to o er you the
best productivity (highly puri ed crystalline
products) and return on investment.
We develop processes with reduced
energy consumption.
Added-value
We develop green and environment-

friendly processes reducing chemicals
and steam consumption.
We implement processes which valorise
by-products:
n enhance the value of vinasses through
crystallization to produce plant
fertilizer
n enhance the value of vinasses through
evaporation to produce cattle food
We provide e uent-free processes.
Recipe
Novasep with Applexion® solutions has
all of the ingredients to develop your
right crystallization and evaporation
solutions. Whatever your needs, crystal-
lizers, evaporators or a complete process
line of crystallization and evaporation,
our engineers will deliver your process to
your taste, with guaranteed performance
and at your required scale.
Other
Our Customer Service (A.S.A.P.) o ers the
highest quality assistance and follow-up.
Novasep Process o ers a broad scope of
services such as:
n Customer Technical Services
(industrial operation assistance, maintenance
contract, training, pilot plants, process
optimization)
n Products

(spare parts, equipment)
Applexion® Evaporation and
Crystallization Solutions:
The Performance you Need!
In chromatographic processes, fractions of desired compound(s) diluted
in solvents (pure and mixtures) are produced. This creates needs for
concentration, evaporation and crystallization operations.
Novasep Process (via Applexion) meets your evaporation and crystallization
requirements. We o er you a complete range of evaporation and crystalliza-
tion processes:
n plate evaporators
n falling  lms
n forced circulation
n Draft Tube Ba e
Applexion® Evaporation Solutions
We design various evaporation and crystallization technologies organized
around cost-e ective thermic schemes:
n multiple e ect
n thermo vapor compression
n mechanical vapor compression
Novasep’s unique team of process engineers:
n design, build and implement a complete unit
combining di erent types of evaporators
adapted to your concentration requirement
n o er a very comprehensive line of evaporators
from lab to industrial scale
n establish a thermic diagram adapted to your
energy considerations
n provide a wide range of evaporators from skid
mounted equipments to very large units (being

able to evaporate over 100 T/h of water)
Applexion® Crystallization Solutions
Novasep’s unique team of process
engineers:
n o er a very comprehensive line of
crystallizers from lab to industrial
scale
n optimize a complete custom-made
design for your crystallization plant
including crystallizer, centrifuge,
vacuum group, and condenser
n provide feasibility studies and
process development meeting
your needs
n integrate crystallization technology into a well-adapted thermic
scheme in order to meet your expectations
n design, build and implement a large range of continuous
crystallization units using high-performing technologies (draft
ba e technology or forced circulation technology) corresponding
to your needs
APPLICATIONS Evaporation Crystallization
Pharmaceutical
industry
• Concentration of
chromatographic
fractions
• E uents recovery for
chromatography
• Crystallization of APIs,
Chiral coumpounds

Waste product
treatment
• E uent concentration
(ra nates, vinasses,
stillages)
• Crystallization of salts
out of e uents, sodium
chlorate, potassium
sulfate and ammonium
sulfate
Bio-industries
• Concentration of sugar
solutions (glucose,
fructose )
• Concentration of organic
acids
• Tagatose crystallization
• Citric acid crystallization

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