PhD Thesis Loe Hui Li @ Felicia Celeste Loe
2010 (HT050567A)
________________________________________________________________________________________
i
BIBLIOGRAPHY
1. Pittenger MF, Mackay
AM, Beck SC, et al.
1999;Multilineage
potential of adult human
mesenchymal stem cells.
Science (5411):143-147.
2. Friedenstein AJ,
Petrakova KV,
Kurolesova AI, et al.
1968;Heterotopic of bone
marrow. Analysis of
precursor cells for
osteogenic and
hematopoietic tissues.
Transplantation (2):230-247.
3. Friedenstein AJ,
Chailakhjan RK, Lalykina
KS. 1970;The
development of fibroblast
colonies in monolayer
cultures of guinea-pig
bone marrow and spleen
cells. Cell Tissue Kinet
(4):393-403.
4. Friedenstein AJ,
Deriglasova UF, Kulagina
NN, et al.
1974;Precursors for
fibroblasts in different
populations of
hematopoietic cells as
detected by the in vitro
colony assay method. Exp
Hematol (2):83-92.
5. Haynesworth S,
Goldberg V, Caplan A, et
al. Diminution of the
number of Mesenchymal
stem cells as a cause for
skeletal aging Y, editors.
American Academy of
Orthopaedic Surgeons.
1994. 79-87 p.
6. Subbanna PKT.
2007;Mesenchymal stem
cells for treating GVHD:
in-vivo fate and optimal
dose. Med Hypotheses
(2):469-470.
7. Simonsen JL, Rosada
C, Serakinci N, et al. 2002;
Telomerase expression
extends the proliferative
life-span and maintains
the osteogenic potential
of human bone marrow
stromal cells. Nat
Biotechnol (6):592-596.
8. Banfi A, Muraglia A,
Dozin B, et al.
2000;Proliferation kinetics
and differentiation
potential of ex vivo
expanded human bone
marrow stromal cells:
Implications for their use
in cell therapy. Exp
Hematol (6):707-715.
9. Hayflick L. 1965;The
limited in vitro lifetime of
human diploid cell strains.
Exp Cell Res :614-636.
10. Stenderup K, Justesen
J, Clausen C, et al.
2003;Aging is associated
with decreased maximal
life span and accelerated
senescence of bone
marrow stromal cells. Bone
(6):919-926.
11. DiGirolamo C, Stokes
D, Colter D.
1999;Propagation and
senescence of human
marrow stromal cells in
culture: A simple colony-
forming assay identifies
samples with the greatest
potential to propagate and
differentiate. Br J Haematol
:275-281.
12. Baksh D, Song L,
Tuan RS. 2004;Adult
mesenchymal stem cells:
characterization,
differentiation, and
application in cell and
gene therapy. J Cell Mol
Med (3):301-316.
13. Rubio D, Garcia-
Castro J, Martín MC, et al.
2005;Spontaneous human
adult stem cell
transformation. Cancer Res
(8):3035-3039.
14. Fuchs E, Tumbar T,
Guasch G.
2004;Socializing with the
neighbors: stem cells and
their niche. Cell (6):769-
778.
15. Morrison SJ, Spradling
AC. 2008;Stem cells and
niches: mechanisms that
promote stem cell
maintenance throughout
life. Cell (4):598-611.
16. Campbell FR.
1987;An electron
microscopic study of
microfibrils of bone
marrow. Scanning Microsc
(4):1711-1714.
PhD Thesis Loe Hui Li @ Felicia Celeste Loe
2010 (HT050567A)
________________________________________________________________________________________
ii
17. Hynes RO.
1987;Integrins: a family of
cell surface receptors. Cell
(4):549-554.
18. Damsky CH, Werb Z.
1992;Signal transduction
by integrin receptors for
extracellular matrix:
cooperative processing of
extracellular information.
Curr Opin Cell Biol (5):772-
781.
19. Farias E, Lu M, Li X,
et al. 2005;Integrin
alpha8beta1-fibronectin
interactions promote cell
survival via PI3 kinase
pathway. Biochem Biophys
Res Commun (1):305-311.
20. Cowles EA, Brailey
LL, Gronowicz GA.
2000;Integrin-mediated
signaling regulates AP-1
transcription factors and
proliferation in
osteoblasts. J Biomed Mater
Res (4):725-737.
21. Taipale J, Keski-Oja J.
1997;Growth factors in
the extracellular matrix.
FASEB J (1):51-59.
22. Rifkin DB, Mazzieri
R, Munger JS, et al.
1999;Proteolytic control
of growth factor
availability. APMIS (1):80-
85.
23. Hildebrand A,
Romarís M, Rasmussen
LM, et al.
1994;Interaction of the
small interstitial
proteoglycans biglycan,
decorin and fibromodulin
with transforming growth
factor beta. Biochem J :527-
534.
24. Iozzo RV. 1999;The
biology of the small
leucine-rich
proteoglycans. Functional
network of interactive
proteins. J Biol Chem
(27):18843-18846.
25. Fogh-Andersen N,
Altura BM, Altura BT, et
al. 1995;Composition of
interstitial fluid. Clin Chem
(10):1522-1525.
26. Ellis RJ.
2001;Macromolecular
crowding: obvious but
underappreciated. Trends
Biochem Sci (10):597-604.
27. Ellis RJ.
2001;Macromolecular
crowding: an important
but neglected aspect of
the intracellular
environment. Curr Opin
Struct Biol (1):114-119.
28. Zimmerman SB,
Minton AP.
1993;Macromolecular
crowding: biochemical,
biophysical, and
physiological
consequences. Annu Rev
Biophys Biomol Struct :27-
65.
29. Chebotareva NA,
Kurganov BI, Livanova
NB. 2004;Biochemical
effects of molecular
crowding. Biochemistry
(Mosc) (11):1239-1251.
30. Minton AP.
2006;How can
biochemical reactions
within cells differ from
those in test tubes? J Cell
Sci (Pt 14):2863-2869.
31. Schofield R. 1978;The
relationship between the
spleen colony-forming
cell and the haemopoietic
stem cell. Blood Cells (1-
2):7-25.
32. Moore KA,
Lemischka IR. 2006;Stem
cells and their niches.
Science (5769):1880-1885.
33. Lemischka IR, Moore
KA. 2003;Stem cells:
interactive niches. Nature
(6960):778-779.
34. Gregory CA, Ylostalo
J, Prockop DJ. 2005;Adult
bone marrow
stem/progenitor cells
(MSCs) are
preconditioned by
microenvironmental
"niches" in culture: a two-
stage hypothesis for
regulation of MSC fate.
Sci STKE (294):pe37.
35. Lareu RR,
Subramhanya KH, Peng
Y, et al. 2007;Collagen
matrix deposition is
dramatically enhanced in
vitro when crowded with
PhD Thesis Loe Hui Li @ Felicia Celeste Loe
2010 (HT050567A)
________________________________________________________________________________________
iii
charged macromolecules:
the biological relevance of
the excluded volume
effect. FEBS Lett
(14):2709-2714.
36. Lareu RR, Arsianti I,
Subramhanya HK, et al.
2007;In vitro
enhancement of collagen
matrix formation and
crosslinking for
applications in tissue
engineering: a preliminary
study. Tissue Eng (2):385-
391.
37. Qian L, Saltzman
WM. 2004;Improving the
expansion and neuronal
differentiation of
mesenchymal stem cells
through culture surface
modification. Biomaterials
(7-8):1331-1337.
38. Koyama H, Raines
EW, Bornfeldt KE, et al.
1996;Fibrillar collagen
inhibits arterial smooth
muscle proliferation
through regulation of
Cdk2 inhibitors. Cell
(6):1069-1078.
39. Mauney JR, Kaplan
DL, Volloch V.
2004;Matrix-mediated
retention of osteogenic
differentiation potential
by human adult bone
marrow stromal cells
during ex vivo expansion.
Biomaterials (16):3233-
3243.
40. van der Flier A,
Sonnenberg A.
2001;Function and
interactions of integrins.
Cell Tissue Res (3):285-298.
41. Mould AP, Askari JA,
Aota SI, et al.
1997;Defining the
topology of integrin
alpha5beta1-fibronectin
interactions using
inhibitory anti-alpha5 and
anti-beta1 monoclonal
antibodies. Evidence that
the synergy sequence of
fibronectin is recognized
by the amino-terminal
repeats of the alpha5
subunit. J Biol Chem
(28):17283-17292.
42. Cukierman E, Pankov
R, Stevens DR, et al.
2001;Taking cell-matrix
adhesions to the third
dimension. Science
(5547):1708-1712.
43. Pierschbacher M,
Hayman C, Ruoslahti E.
1984;nd Variants of the
cell recognition site of
fibronectin that retain
attachment-promoting
activity. Proc Natl Acad Sci
USA :1224-1227.
44. Danilov YN, Juliano
RL. 1989;(Arg-Gly-Asp)n-
albumin conjugates as a
model substratum for
integrin-mediated cell
adhesion. Exp Cell Res
(1):186-196.
45. Flaim C, Chien S,
Bhatia S. 1995;An
extracellular matrix
microarray for probing
cellular differentiation.
Nature Methods 2
FoghAndersen Composition of
Interstitial Fluid Clin Chem
1522 (10):119-125.
46. Engler AJ, Sen S,
Sweeney HL, et al.
2006;Matrix elasticity
directs stem cell lineage
specification. Cell (4):677-
689.
47. Bader A, Knop E,
Kern A, et al. 1996;3-D
coculture of hepatic
sinusoidal cells with
primary hepatocytes-
design of an organotypical
model. Exp Cell Res
(1):223-233.
48. Kleinman HK,
McGarvey ML, Liotta LA,
et al. 1982;Isolation and
characterization of type
IV procollagen, laminin,
and heparan sulfate
proteoglycan from the
EHS sarcoma. Biochemistry
(24):6188-6193.
49. Ahmed TAE, Dare
EV, Hincke M.
2008;Fibrin: a versatile
scaffold for tissue
engineering applications.
Tissue engineering. Part B,
Reviews (2):199-215.
50. Ito K, Yamada Y,
Naiki T, et al.
2006;Simultaneous
implant placement and
bone regeneration around
PhD Thesis Loe Hui Li @ Felicia Celeste Loe
2010 (HT050567A)
________________________________________________________________________________________
iv
dental implants using
tissue-engineered bone
with fibrin glue,
mesenchymal stem cells
and platelet-rich plasma.
Clin Oral Implants Res
(5):579-586.
51. Awad HA, Butler DL,
Harris MT, et al. 2000;In
vitro characterization of
mesenchymal stem cell-
seeded collagen scaffolds
for tendon repair: effects
of initial seeding density
on contraction kinetics. J
Biomed Mater Res (2):233-
240.
52. Schmeichel KL,
Bissell MJ. 2003;Modeling
tissue-specific signaling
and organ function in
three dimensions. J Cell Sci
(Pt 12):2377-2388.
53. Bissell MJ, Barcellos-
Hoff MH. 1987;The
influence of extracellular
matrix on gene
expression: is structure
the message? J Cell Sci
Suppl :327-343.
54. Bissell MJ, Aggeler J.
1987;Dynamic reciprocity:
how do extracellular
matrix and hormones
direct gene expression?
Prog Clin Biol Res :251-262.
55. Lutolf MP, Hubbell
JA. 2005;Synthetic
biomaterials as instructive
extracellular
microenvironments for
morphogenesis in tissue
engineering. Nat Biotechnol
(1):47-55.
56. Cushing MC, Anseth
KS. 2007;Materials
science. Hydrogel cell
cultures. Science
(5828):1133-1134.
57. Lutolf MP.
2009;Integration column:
artificial ECM: expanding
the cell biology toolbox in
3D. Integrative biology :
quantitative biosciences from
nano to macro (3):235-241.
58. Zhou L, Lai ZT, Lu
MK, et al.
2008;Expression and
hydroxylamine cleavage
of thymosin alpha 1
concatemer. Journal of
biomedicine & biotechnology
:736060.
59. Matsubara T,
Tsutsumi S, Pan H, et al.
2004;A new technique to
expand human
mesenchymal stem cells
using basement
membrane extracellular
matrix. Biochem Biophys Res
Commun (3):503-508.
60. Chen XD, Dusevich
V, Feng JQ, et al.
2007;Extracellular matrix
made by bone marrow
cells facilitates expansion
of marrow-derived
mesenchymal progenitor
cells and prevents their
differentiation into
osteoblasts. J Bone Miner
Res (12):1943-1956.
61. Grünert M,
Dombrowski C,
Sadasivam M, et al.
2007;Isolation of a native
osteoblast matrix with a
specific affinity for BMP2.
J Mol Histol (5):393-404.
62. van den Bos C, Mosca
JD, Winkles J, et al.
1997;Human
mesenchymal stem cells
respond to fibroblast
growth factors. Hum Cell
(1):45-50.
63. Hanada K, Dennis JE,
Caplan AI.
1997;Stimulatory effects
of basic fibroblast growth
factor and bone
morphogenetic protein-2
on osteogenic
differentiation of rat bone
marrow-derived
mesenchymal stem cells. J
Bone Miner Res (10):1606-
1614.
64. Akino K, Mineta T,
Fukui M, et al. 2003;Bone
morphogenetic protein-2
regulates proliferation of
human mesenchymal
stem cells. Wound Repair
Regen (5):354-360.
65. Xiao Z, Zhang W,
Yang Y, et al. 2008;Single-
molecule diffusion study
of activated EGFR
implicates its endocytic
pathway. Biochem Biophys
Res Commun (2):730-734.
66. Friedl A, Chang Z,
PhD Thesis Loe Hui Li @ Felicia Celeste Loe
2010 (HT050567A)
________________________________________________________________________________________
v
Tierney A, et al.
1997;Differential binding
of fibroblast growth
factor-2 and -7 to
basement membrane
heparan sulfate:
comparison of normal
and abnormal human
tissues. Am J Pathol
(4):1443-1455.
67. Yayon A, Klagsbrun
M, Esko JD, et al.
1991;Cell surface,
heparin-like molecules are
required for binding of
basic fibroblast growth
factor to its high affinity
receptor. Cell (4):841-848.
68. Dombrowski C, Song
SJ, Chuan P, et al.
2009;Heparan sulfate
mediates the proliferation
and differentiation of rat
mesenchymal stem cells.
Stem Cells Dev (4):661-670.
69. Edlund U, Dånmark
S, Albertsson AC. 2008;A
strategy for the covalent
functionalization of
resorbable polymers with
heparin and
osteoinductive growth
factor. Biomacromolecules
(3):901-905.
70. Benoit DSW, Durney
AR, Anseth KS. 2007;The
effect of heparin-
functionalized PEG
hydrogels on three-
dimensional human
mesenchymal stem cell
osteogenic differentiation.
Biomaterials (1):66-77.
71. Serakinci N, Guldberg
P, Burns JS, et al.
2004;Adult human
mesenchymal stem cell as
a target for neoplastic
transformation. Oncogene
(29):5095-5098.
72. Minton AP. 2001;The
influence of
macromolecular crowding
and macromolecular
confinement on
biochemical reactions in
physiological media. J Biol
Chem (14):10577-10580.
73. Minton AP.
1993;Macromolecular
crowding and molecular
recognition. J Mol Recognit
(4):211-214.
74. Grisendi G, Annerén
C, Cafarelli L, et al.
2010;GMP-manufactured
density gradient media for
optimized mesenchymal
stromal/stem cell
isolation and expansion.
Cytotherapy
75. Du F, Zhou Z, Mo
ZY, et al. 2006;Mixed
macromolecular crowding
accelerates the refolding
of rabbit muscle creatine
kinase: implications for
protein folding in
physiological
environments. J Mol Biol
(3):469-482.
76. Harve KS,
Vigneshwar R,
Rajagopalan R, et al.
2008;Macromolecular
crowding in vitro as
means of emulating
cellular interiors: when
less might be more. Proc
Natl Acad Sci U S A
(51):E119; author reply
E120.
77. Batra J, Xu K, Zhou
HX. 2009;Nonadditive
effects of mixed crowding
on protein stability.
Proteins (1):133-138.
78. Harve KS, Lareu R,
Rajagopalan R, et al.
2010;Understanding how
the crowded interior of
cells stabilizes
DNA/DNA and
DNA/RNA hybrids-in
silico predictions and in
vitro evidence. Nucleic
Acids Res (1):172-181.
79. Chen CZC, Peng YX,
Wang ZB, et al. 2009;The
Scar-in-a-Jar: studying
potential antifibrotic
compounds from the
epigenetic to extracellular
level in a single well. Br J
Pharmacol (5):1196-1209.
80. Harve K, Lareu R,
Rajagopalan R, et al.
2006;Macromolecular
Crowding in Biological
Systems: Dynamic Light
Scattering (DLS) to
quantify the Excluded
Volume Effect (EVE).
Biophysical Reviews and
Letters-:. (3):317-325.
81. Prockop DJ, Sieron
PhD Thesis Loe Hui Li @ Felicia Celeste Loe
2010 (HT050567A)
________________________________________________________________________________________
vi
AL, Li SW.
1998;Procollagen N-
proteinase and
procollagen C-proteinase.
Two unusual
metalloproteinases that
are essential for
procollagen processing
probably have important
roles in development and
cell signaling. Matrix Biol
(7):399-408.
82. Lilla J, Stickens D,
Werb Z.
2002;Metalloproteases
and adipogenesis: a
weighty subject. Am J
Pathol (5):1551-1554.
83. Mariman ECM, Wang
P. 2010;Adipocyte
extracellular matrix
composition, dynamics
and role in obesity. Cell
Mol Life Sci (8):1277-1292.
84. Auger FA, Berthod F,
Moulin V, et al.
2004;Tissue-engineered
skin substitutes: from in
vitro constructs to in vivo
applications. Biotechnol
Appl Biochem (Pt 3):263-
275.
85. Bateman JF, Cole
WG, Pillow JJ, et al.
1986;Induction of
procollagen processing in
fibroblast cultures by
neutral polymers. J Biol
Chem (9):4198-4203.
86. Bateman JF, Golub
SB. 1990;Assessment of
procollagen processing
defects by fibroblasts
cultured in the presence
of dextran sulphate.
Biochem J (3):573-577.
87. Noble BS, Dean V,
Loveridge N, et al.
1995;Dextran sulfate
promotes the rapid
aggregation of porcine
bone-marrow stromal
cells. Bone (4):375-382.
88. Mauney JR, Volloch
V, Kaplan DL.
2005;Matrix-mediated
retention of adipogenic
differentiation potential
by human adult bone
marrow-derived
mesenchymal stem cells
during ex vivo expansion.
Biomaterials (31):6167-
6175.
89. Bissell MJ, Hall HG,
Parry G. 1982;How does
the extracellular matrix
direct gene expression? J
Theor Biol (1):31-68.
90. Nelson CM, Bissell
MJ. 2006;Of extracellular
matrix, scaffolds, and
signaling: tissue
architecture regulates
development,
homeostasis, and cancer.
Annu Rev Cell Dev Biol
:287-309.
91. Bissell MJ, Inman J.
2008;Reprogramming
stem cells is a
microenvironmental task.
Proc Natl Acad Sci U S A
(41):15637-15638.
92. Xu R, Boudreau A,
Bissell MJ. 2009;Tissue
architecture and function:
dynamic reciprocity via
extra- and intra-cellular
matrices. Cancer Metastasis
Rev (1-2):167-176.
93. Maxwell CA,
McCarthy J, Turley E.
2008;Cell-surface and
mitotic-spindle RHAMM:
moonlighting or dual
oncogenic functions? J
Cell Sci (Pt 7):925-932.
94. Sanderson RD, Yang
Y, Suva LJ, et al.
2004;Heparan sulfate
proteoglycans and
heparanase partners in
osteolytic tumor growth
and metastasis. Matrix Biol
(6):341-352.
95. Sottile J, Hocking DC.
2002;Fibronectin
polymerization regulates
the composition and
stability of extracellular
matrix fibrils and cell-
matrix adhesions. Mol Biol
Cell (10):3546-3559.
96. Keely PJ, Wu JE,
Santoro SA. 1995;The
spatial and temporal
expression of the alpha 2
beta 1 integrin and its
ligands, collagen I,
collagen IV, and laminin,
suggest important roles in
mouse mammary
morphogenesis.
Differentiation (1):1-13.
PhD Thesis Loe Hui Li @ Felicia Celeste Loe
2010 (HT050567A)
________________________________________________________________________________________
vii
97. Talhouk RS, Chin JR,
Unemori EN, et al.
1991;Proteinases of the
mammary gland:
developmental regulation
in vivo and vectorial
secretion in culture.
Development (2):439-449.
98. Taddei I, Deugnier
MA, Faraldo MM, et al.
2008;Beta1 integrin
deletion from the basal
compartment of the
mammary epithelium
affects stem cells. Nat Cell
Biol (6):716-722.
99. Woodward TL,
Mienaltowski AS, Modi
RR, et al.
2001;Fibronectin and the
alpha(5)beta(1) integrin
are under developmental
and ovarian steroid
regulation in the normal
mouse mammary gland.
Endocrinology (7):3214-
3222.
100. Salasznyk RM, Klees
RF, Williams WA, et al.
2007;Focal adhesion
kinase signaling pathways
regulate the osteogenic
differentiation of human
mesenchymal stem cells.
Exp Cell Res (1):22-37.
101. Salasznyk RM, Klees
RF, Boskey A, et al.
2007;Activation of FAK
is necessary for the
osteogenic differentiation
of human mesenchymal
stem cells on laminin-5. J
Cell Biochem (2):499-514.
102. Lozito TP, Kuo CK,
Taboas JM, et al.
2009;Human
mesenchymal stem cells
express vascular cell
phenotypes upon
interaction with
endothelial cell matrix. J
Cell Biochem (4):714-722.
103. Lozito TP, Taboas
JM, Kuo CK, et al.
2009;Mesenchymal stem
cell modification of
endothelial matrix
regulates their vascular
differentiation. J Cell
Biochem (4):706-713.
104. Kuhn NZ, Tuan RS.
2010;Regulation of
stemness and stem cell
niche of mesenchymal
stem cells: implications in
tumorigenesis and
metastasis. J Cell Physiol
(2):268-277.
105. Tsai MS, Hwang SM,
Chen KD, et al.
2007;Functional network
analysis of the
transcriptomes of
mesenchymal stem cells
derived from amniotic
fluid, amniotic membrane,
cord blood, and bone
marrow. Stem Cells
(10):2511-2523.
106. Rosen ED,
Spiegelman BM.
2000;Molecular regulation
of adipogenesis. Annu Rev
Cell Dev Biol :145-171.
107. McBeath R, Pirone
DM, Nelson CM, et al.
2004;Cell shape,
cytoskeletal tension, and
RhoA regulate stem cell
lineage commitment. Dev
Cell (4):483-495.
108. Gregoire FM, Smas
CM, Sul HS.
1998;Understanding
adipocyte differentiation.
Physiol Rev (3):783-809.
109. Alexander CM,
Selvarajan S, Mudgett J, et
al. 2001;Stromelysin-1
regulates adipogenesis
during mammary gland
involution. J Cell Biol
(4):693-703.
110. Zizola CF, Julianelli
V, Bertolesi G, et al.
2007;Role of versican and
hyaluronan in the
differentiation of 3T3-L1
cells into preadipocytes
and mature adipocytes.
Matrix Biol (6):419-430.
111. Gimble JM, Morgan
C, Kelly K, et al.
1995;Bone
morphogenetic proteins
inhibit adipocyte
differentiation by bone
marrow stromal cells. J
Cell Biochem (3):393-402.
112. Cawthon RM.
2002;Telomere
measurement by
quantitative PCR. Nucleic
Acids Res (10):e47.
113. Boulay JL, Reuter J,
PhD Thesis Loe Hui Li @ Felicia Celeste Loe
2010 (HT050567A)
________________________________________________________________________________________
viii
Ritschard R, et al.
1999;Gene dosage by
quantitative real-time
PCR. Biotechniques (2):228-
30, 232.
114. Minguell JJ, Erices A,
Conget P.
2001;Mesenchymal stem
cells. Exp Biol Med
(Maywood) (6):507-520.
115. Aratani Y, Kitagawa
Y. 1988;Enhanced
synthesis and secretion of
type IV collagen and
entactin during adipose
conversion of 3T3-L1
cells and production of
unorthodox laminin
complex. J Biol Chem
(31):16163-16169.
116. Mitsi M, Forsten-
Williams K,
Gopalakrishnan M, et al.
2008;A catalytic role of
heparin within the
extracellular matrix. J Biol
Chem (50):34796-34807.
117. Wilson EL, Rifkin
DB, Kelly F, et al.
1991;Basic fibroblast
growth factor stimulates
myelopoiesis in long-term
human bone marrow
cultures. Blood (5):954-960.
118. Tsutsumi S, Shimazu
A, Miyazaki K, et al.
2001;Retention of
multilineage
differentiation potential of
mesenchymal cells during
proliferation in response
to FGF. Biochem Biophys
Res Commun (2):413-419.
119. Sasada R, Seno M,
Watanabe T, et al.
1991;Expression of
modified bFGF cDNAs
in mammalian cells. Ann
N Y Acad Sci :149-160.
120. Kolf CM, Cho E,
Tuan RS.
2007;Mesenchymal
stromal cells. Biology of
adult mesenchymal stem
cells: regulation of niche,
self-renewal and
differentiation. Arthritis
Res Ther (1):204.
121. Owen M, Peck W.
1985;Lineage of
osteogenic cells and their
relationship to the stromal
system. In ed Bone and
MineralAmsterdam Elsevier
pp :1-25.
122. Owen M.
1988;Marrow stromal
stem cells. J Cell Sci Suppl
:63-76.
123. Beresford JN.
1989;Osteogenic stem
cells and the stromal
system of bone and
marrow. Clin Orthop Relat
Res (240):270-280.
124. Caplan AI.
1991;Mesenchymal stem
cells. J Orthop Res (5):641-
650.
125. Caplan A, Fink D,
Goto T, et al.
1993;Mesenchymal stem
cells and tissue repair. In
ed The Anterior Cruciate
Ligament Current and Future
Concepts New York Raven
Press Ltd pp :405-417.
126. Wakitani S, Saito T,
Caplan AI.
1995;Myogenic cells
derived from rat bone
marrow mesenchymal
stem cells exposed to 5-
azacytidine. Muscle Nerve
(12):1417-1426.
127. Dennis JE, Caplan
AI. 1996;Differentiation
potential of conditionally
immortalized
mesenchymal progenitor
cells from adult marrow
of a H-2Kb-tsA58
transgenic mouse. J Cell
Physiol (3):523-538.
128. Mackay AM, Beck
SC, Murphy JM, et al.
1998;Chondrogenic
differentiation of cultured
human mesenchymal
stem cells from marrow.
Tissue Eng (4):415-428.
129. Beresford JN,
Graves SE, Smoothy CA.
1993;Formation of
mineralized nodules by
bone derived cells in vitro:
a model of bone
formation? Am J Med
Genet (2):163-178.
130. Greenspan P, Mayer
EP, Fowler SD. 1985;Nile
red: a selective fluorescent
stain for intracellular lipid
droplets. J Cell Biol
PhD Thesis Loe Hui Li @ Felicia Celeste Loe
2010 (HT050567A)
________________________________________________________________________________________
ix
(3):965-973.
131. Hamilton R,
Campbell FR.
1991;Immunochemical
localization of
extracellular materials in
bone marrow of rats.
Anat Rec (2):218-224.
132. Wallace DG,
Rosenblatt J.
2003;Collagen gel systems
for sustained delivery and
tissue engineering. Adv
Drug Deliv Rev (12):1631-
1649.
133. Globus RK, Doty
SB, Lull JC, et al.
1998;Fibronectin is a
survival factor for
differentiated osteoblasts.
J Cell Sci :1385-1393.
134. Carvalho RS,
Kostenuik PJ, Salih E, et
al. 2003;Selective adhesion
of osteoblastic cells to
different integrin ligands
induces osteopontin gene
expression. Matrix Biol
(3):241-249.
135. Spiegelman BM,
Ginty CA.
1983;Fibronectin
modulation of cell shape
and lipogenic gene
expression in 3T3-
adipocytes. Cell (3 Pt
2):657-666.
136. Pierleoni C,
Verdenelli F, Castellucci
M, et al.
1998;Fibronectins and
basal lamina molecules
expression in human
subcutaneous white
adipose tissue. Eur J
Histochem (3):183-188.
137. Kapuscinski J.
1995;DAPI: a DNA-
specific fluorescent probe.
Biotech Histochem (5):220-
233.
138. Cooper JA.
1987;Effects of
cytochalasin and
phalloidin on actin. J Cell
Biol (4):1473-1478.
139. Quéméneur E,
Guthapfel R, Gueguen P.
1994;A major
phosphoprotein of the
endoplasmic reticulum is
protein disulfide
isomerase. J Biol Chem
(8):5485-5488.
140. Bouwman F, Renes
J, Mariman E. 2004;A
combination of protein
profiling and isotopomer
analysis using matrix-
assisted laser
desorption/ionization-
time of flight mass
spectrometry reveals an
active metabolism of the
extracellular matrix of
3T3-L1 adipocytes.
Proteomics (12):3855-3863.