9/10/2012
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Chapter 10
Review of Human Systems
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Lesson 10.1
Human Anatomy and
Terminology
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Learning Objectives
• Discuss the importance of human anatomy as
it relates to the paramedic profession.
• Describe anatomical position.
• Properly interpret anatomical directional
terms and body planes.
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Learning Objectives
• List the structures that compose axial and
appendicular regions of the body.
• Define the divisions of the abdominal region.
• List the three major body cavities.
• Describe the contents of the three major
body cavities.
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Human Anatomy
• Study of how the human body is organized
• Reason for anatomy knowledge
– To assess patient by body region
– To help communicate well with other health
team members
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Anatomical Position
• Directional terms for human body, used by
medical field
• Person standing erect with feet, palms
facing examiner
• Supine position
– Lying on back, face up
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Anatomical Position
• Prone position
– Lying on stomach, face down
• Lateral recumbent position
– Lying on left, right side
• Regardless, patient’s position always
conveyed, reference anatomical position
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Directional Terms
• Up, down, front, back, right, left
• Always refer to patient, not examiner
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Anatomical Planes
• Internal body structure relationships classified into
anatomical planes
• Viewed as imaginary straight‐line divisions of the
body
• Sagittal plane: runs vertically through middle, creates
right, left sections
• Parasagittal plane: to one side of midline
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Anatomical Planes
• Transverse plane
– Horizontal division, divides body into top,
bottom sections
– Superior, inferior sections
• Coronal, frontal plane
– Divides body into front, back
– Anterior, posterior sections
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Body Regions
• Appendicular region
– Limbs
– Extremities
• Axial region
– Head
– Neck
– Thorax
– Abdomen
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Body Regions
• Abdomen has four quadrants
– Upper right
– Lower right
– Upper left
– Lower left
– Run horizontally through umbilicus
– Run vertically from xiphoid process through
symphysis pubis
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Body Cavities: Thoracic
• Thoracic cavity
– Divided into two portions by midline
structure/mediastinum
– Includes trachea, esophagus, thymus, heart,
great vessels
– Lungs located on either side of mediastinum
– Surrounded by rib cage
– Separated from abdominal cavity by diaphragm
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Body Cavities: Abdominal, Pelvic
• Contains two pleural cavities (contain lungs)
and pericardial cavity (contains heart)
– Cavities lined with serous membrane
– If serous membrane contacts organ, is visceral
– If serous membrane contacts cavity wall,
is parietal
– Thin lubricating fluid film produced by
membranes, reduces friction
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Body Cavities: Abdominal, Pelvic
• Lined with thin sheet, membranous tissue,
secretes serous fluid
• Visceral peritoneum
– Serous membrane that covers abdominal organs
• Parietal peritoneum
– Serous membrane that covers body cavity wall
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Body Cavities: Abdominal, Pelvic
• Mesentery
– Peritoneal organs held in place by
connective tissue
– Holds some abdominal organs to body wall, offers
pathway for nerves, vessels to reach organs
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Body Cavities: Abdominal, Pelvic
• Retroperitoneal
– Abdominopelvic organs with no mesentery,
peritoneum, are retroperitoneal
– Behind peritoneum
– Include kidneys, adrenal glands, pancreas, colon
portions, urinary bladder
• Pelvic cavity enclosed by pelvis bones
• Referred to collectively as peritoneal or
abdominopelvic cavity
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Lesson 10.2
Cell Structure
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Learning Objectives
• Discuss the functions of the following cellular
structures: the cytoplasmic membrane, the
cytoplasm (and organelles), and the nucleus.
• Describe the process by which human
cells reproduce.
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Cell Structure
• Cells are basic life unit
– Highly organized, composed of protoplasm,
living matter
– Main parts are cytoplasmic membrane (plasma
membrane), cytoplasm, nucleus
• Cytoplasmic membrane
– Encloses cytoplasm, forms outer cell boundary
– Two layers of phosphate‐containing fat
molecules, phospholipids
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Cell Structure
• Form fluid framework for membrane
– Substances outside membrane, extracellular
(outside cell), intercellular (between cells)
– Substances inside membrane, intracellular
– Enclose, support cell contents, regulate what
moves into, out of cell
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Cell Structure
• Central layer, lipid bilayer
– Composed of double layer lipid molecules
– Liquid quality
– Protein molecules “float” on inner, outer surfaces
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Cytoplasm
• Lies between cytoplasmic membrane
and nucleus
– Nucleus is round structure in cell center
• Organelles
– Specialized structures in cell
– Perform functions important for cell survival
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Cytoplasm
• Endoplasmic reticulum
– Chain of connecting sacs or canals, winds
through cytoplasm
– Serves as tiny circulatory system
– Tubular passages, canals carry proteins, other
substances from one area to another
– Smooth endoplasmic reticulum
– Rough endoplasmic reticulum
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Cytoplasm
• Ribosomes
– “Factories” in which protein is synthesized
– Macromolecules of protein, and ribonucleic acid
(RNA), composed of thousands of atoms
– Bound to endoplasmic reticulum, also found free
in cytoplasm
– Form complexes with RNA strands, which, through
genetic code, provide blueprint for new protein
– Individual amino acids attach in long chains with
peptide bonds to form new proteins
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Cytoplasm
• Golgi apparatus
– Concentrates, packages materials for secretion
from cell
– Tiny sacs composed of smooth endoplasmic
reticulum
– Sacs stacked one on the other near nucleus
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Cytoplasm
• Golgi apparatus sometimes chemically
modifies proteins
– Synthesizes, attaches carbohydrate molecules to
proteins, forms glycoproteins or attaches lipids to
proteins, forms lipoproteins
– Concentrated globules move slowly outward to
and through cell membrane, then break open,
spill contents
– Example product of mucus
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Cytoplasm
• Lysosomes
– Membranous‐walled organelles
– Contain enzymes to function as intracellular
digestive systems
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Cytoplasm
• Lysosomes include those that digest nucleic
acids, proteins, polysaccharides, lipids
– Certain WBCs (leukocytes) have large numbers of
lysosomes that contain enzymes to digest
engulfed bacteria
– If tissues damaged, enzymes may escape from
ruptured lysosome sacs into cytoplasm, digesting
damaged and healthy cells
– Digest organelles of cell that are no longer
functional (autophagia)
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Cytoplasm
• Mitochondria
– Power plants of cell
– Found throughout the cell
– Site of aerobic oxidation
– Energy derived from efficient metabolism of
nutrients and oxygen used to synthesize high‐
energy triphosphate bonds
– Triphosphate bonds are energy source for
muscles, nerves, overall body function
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Your patient has bad lung disease
and poor oxygenation. What effect
will this have on cellular
energy production?
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Cytoplasm
• Centrioles
– Paired, rod‐shaped organelles that lie at right
angles to each other in specialized cytoplasm
zone (centrosome)
– Composed of microtubules that play important
role in cell division process
– All human cells, at some point, contain nucleus in
which cell’s genetic material is located
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Nucleus
• Nucleus
– All human cells contain nucleus
– Contain genetic material
– Controls all organelle in cytoplasm
– Spherical, elongated, lobed, depending on
cell type
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Nucleus
• Some cells lose the nucleus as they develop
– Red blood cells
– Erythrocytes
• Some cells have more than one nucleus
• Most categorizing feature of cell is
presence/absence of nucleus
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Nucleus
• Relatively large structure, not always near
cell’s center
• Surrounded by nuclear membrane
– Encloses nucleoplasm, special type of protoplasm
• Nucleoplasm contains nucleolus,
chromatin granules
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Nucleus
• Nucleolus consists of deoxyribonucleic
acid (DNA)
– “Programs” RNA formation and protein, makes
ribosomes
– Ribosomes migrate through nuclear membrane
into cell’s cytoplasm, produce proteins
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Nucleus
• Chromatin granules
– Threadlike structures made up of proteins, DNA
– During cell division, condense, form 23 pairs of
chromosomes in human cells
– Nuclear DNA information determines most
chemical events occurring within cell
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Nucleus
• Basic functions are cell division, genetic
information control
• Not all cells capable of continuous division
• Some cells (nerve cells) cannot reproduce
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Major Cell Classes
• Free‐living cells of multicellular, “social”
organisms divided into two major classes
• Divided by how genetic material is organized
inside them
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Major Cell Classes
• Eukaryotes
– “True nucleus”
– Larger than prokaryotes
– Have more extensive intracellular anatomy
– Have separate membrane‐bound nucleus that
holds genetic material (chromosomes, DNA)
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Major Cell Classes
• Eukaryotes
– Fluid filling is divided into nucleoplasm, cytoplasm
– Nucleoplasm is inside nuclear membrane
– Cytoplasm is outside nuclear membrane
– Nearly all human body cells, living organism cells
are eukaryotes
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Major Cell Classes
• Prokaryote
– “Before nucleus”
– Genetic material, enzymes required for energy
production, cell growth, cell division, are
contained in cytoplasm
– Cytoplasm surrounded by plasma membrane
– Simple internal organization
– Do not have nucleus bound by plasma membrane
– DNA attached to plasma membrane
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Chief Cellular Functions
• Through differentiation (maturation), cells
become specialized
– Act in concert with other cells to perform more
complex task
– RBCs transport respiratory gases around body
– Pancreatic cells synthesize, secrete large
quantities of digestive enzymes, which are
required to break down foods
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Chief Cellular Functions
• Movement (muscle cells)
• Conductivity (nerve cells)
• Metabolic absorption (kidney, intestinal cells)
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Chief Cellular Functions
•
•
•
•
Secretion (mucous gland cells)
Excretion (all cells)
Respiration (all cells)
Reproduction (most cells)
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What type of cells regenerate?
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Cell Reproduction
• All human cells reproduce by mitosis process
– Exception is reproductive (sex) cells
– Cells divide to multiply: one cell divides, forms two
cells
– Many cell types (epithelial, liver, bone marrow)
undergo cell division throughout individual’s life
– Other cell types (nerve, skeletal muscle) divide
until near birth
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Lesson 10.3
Tissues
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Learning Objective
• Differentiate and describe the following tissue
types: epithelial tissue, connective tissue,
muscle tissue, and nervous tissue.
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Tissues
• Epithelial tissue
– Covers surfaces, forms structures derived from
body surfaces
– Consists almost entirely of cells with little/no
intercellular material between them
– Forms continuous sheets, contain no blood vessels
– Covers outside body
– Lines digestive tract, vessels, many body cavities
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Tissues
• Epithelial tissue is classified by cell shape
• Squamous
– Flat, scalelike
• Cuboidal
– Cube shaped
• Columnar
– More tall than wide
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Tissues
• Epithelial tissue is classified by arrangement
• Simple
– Single layer cells
– Same shape
• Stratified
– Multiple layers
– Same shape
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Connective Tissue
• Most abundant type
• Most widely distributed type
• Consists of cells separated from each other by
intercellular material (extracellular matrix)
• Nonliving matrix gives fundamental
characteristics, basis for separating connective
tissue into subgroups
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Connective Tissue
• Areolar connective tissue
– Loose tissue
– Delicate fiber webs, variety of cells embedded in
matrix of soft, sticky gel
– “Loose packing” material of most organs,
other tissues
– Attaches skin to underlying tissues
– Contains major protein fiber types: collagen,
reticulum, elastin
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Connective Tissue
• Adipose tissue, fat tissue
– Specialized tissue, stores lipids
– Lipids take up less space per calorie than
carbohydrates, proteins
– Acts as insulator, protector, energy storage site
• Fibrous connective tissue
– Bundles strong, white collagenous fibers in
parallel rows
– Compose tendons
– Characterized by strength, inelasticity
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Connective Tissue
• Cartilage
– Cartilage cells, chondrocytes
– Located in tiny spaces distributed throughout
somewhat rigid matrix
– Makeup varies by location, ultimate role
– Makes up part of skeleton, covers articulating
bone surfaces
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Connective Tissue
• Cartilage
– Forms major skeletal tissue of embryo before
being replaced by bony tissue
– Type depends on relative amounts of collagen,
elastin, ground substance
– Blood vessels do not penetrate, heals slowly
after injury
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Connective Tissue
• Bone
– Highly specialized form of hard, connective tissue
– Consists of living cells, mineralized matrix
– Matrix strength, rigidity allow support, tissue,
organ protection
– Classified by shape
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Bone
• Long bones, longer than wide
– Humerus
– Ulna
– Femur
– Tibia
– Fibula
– Phalanges
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Bone
• Short bones, broad as they are long
– Carpal wrist bones
– Tarsal ankle bones
• Flat bones, thin, flattened shape
– Skull bones
– Ribs
– Sternum
– Scapulae
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Bone
• Irregular bones, do not fit in other categories
– Vertebrae
– Facial bones
• Growing long bones
– Diaphysis (shaft)
– Epiphysis, at bone end
– Epiphyseal plate, growth plate
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Bone
• Epiphyseal plate, growth plate
– Bone elongation site
– Bone growth stops, plate becomes ossified, called
epiphyseal line
– Injury can impair bone growth if not recognized,
treated properly
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Intraosseous infusion is a critical intervention that
can save a life. Intraosseous infusion is used to
administer fluids and drugs. This infusion requires
the insertion of a needle into the bone of the leg.
Why could the failure to identify anatomical
landmarks or place the needle correctly in the
epiphysis in a child be harmful?
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Bone
• Contain large, smaller cavities
– Larger cavity, medullary cavity in diaphysis
– Smaller cavity, long bone epiphyses, throughout
some bone interiors
– Spaces filled with yellow marrow (mainly adipose
tissue) or red marrow (blood formation site)
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Bone
• Blood supply to most bones, excellent
– Some bones, including tibia, sternum are suitable
choices for venous access via intraosseous infusion
• Classified as cancellous/spongy bone,
compact bone
– Cancellous bone has spaces between bone plates,
resembles sponge
– Compact bone is essentially solid
• Rich blood supply, repairs itself
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Connective Tissue
• Blood
– Unique connective tissue as matrix between cells
is liquid
– Liquid matrix allows rapid flow through body
– Carries nutrients, oxygen, waste products,
other materials
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Connective Tissue
• Hemopoietic tissue
– In marrow cavities of bone
– In spleen, tonsils, lymph nodes
– Responsible for formation of blood cells of
lymphatic system cells, which are important
defense against disease
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