DiagnTher.2017[Epubbeforeprint].
Fetalaorticdistensibilitymaybemeasuredusing
speckletrackingofthethoracicaortic
circumference—thefractionalareachange.The
relationshipbetweenfetalbloodpressureand
thismeasureisvalidatedinananimalmodelin
thispaper.
YeoL,RomeroR.Colorandpowerdoppler
combinedwithfetalintelligentnavigation
echocardiography(FINE)toevaluatethefetal
heart.UltrasoundObstetGynecol.
2017;50(4):476–491.
FetalIntelligentNavigationEchocardiography
(FINE)isanovelcomputer-aidedmethod
developedbytheauthorstoassistin
interpretationofthefetalheartfromthree
dimensionalvolumesofbycreatingaseriesof
standardechocardiographyviews.
YeoL,RomeroR.Prenataldiagnosisof
hypoplasticleftheartandcoarctationoftheaorta
withcolordopplerFINE.UltrasoundObstet
Gynecol.2017;50(4):543–544.
Thispaperbuildsonpreviousworkbytheauthors
anddescribeshowcongenitalheartdefectsmay
berecognisedusingfetalintelligentnavigation
echocardiographycombinedwithcolorDoppler.
References
1.KellerBB,HuN,TinneyJP.Embryonic
ventriculardiastolicandsystolicpressurevolumerelation.CardiolYoung.1994;4:19–27.
2.KirbyML.Developmentofthefetalheart.Polin
RA,FoxWW.FetalandNeonatalPhysiology.
Saunders:Philadelphia,PA;1992:589–597.
3.JacksonM,ConnellMG,SmithA.Development
ofthecollagennetworkofthehumanfetal
myocardium:animmunohistochemicalstudy.Int
JCardiol.1993;41:77–86.
4.MitchellJL,CuneoBF,EtheridgeSP,etal.Fetal
heartratepredictorsoflongQTsyndrome.
Circulation.2012;126(23):2688–2695.
5.HuN,ConnuckDM,KellerBB,ClarkEB.
Diastolicfillingcharacteristicsinthestage12to
27chickembryoventricle.PediatrRes.
1991;29:334–337.
6.BensonDWJr,HughesSF,HuN,ClarkEB.
Effectofheartrateincreaseondorsalaorticflow
beforeandaftervolumeloadinginthestage24
chickembryo.PediatrRes.1999;26:245–249.
7.VaccaroH,AmorF,LeytonM,SepulvedaW.
Arrhythmiainearlypregnancy:apredictorof
first-trimesterpregnancyloss.UltrasoundObstet
Gynecol.1998;12:248–251.
8.FineC,StJohnSuttonMG,CartierMS,
DoubiletPM.Variationinheartrateinthe
normalhumanfetusduringandafter
cardiogenesis.Circulation.
1988;78(supplII):397.
9.KirbyML,McKenzieJW,WeidmanTA.
Developinginnervationofthechickheart:a
histofluorescenceandlightmicroscopicstudyof
sympatheticinnervation.AnatRec.
1980;196:333–340.
10.MarkowitzC.Responseofexplantedembryonic
cardiactissuestoepinephrineandacetylcholine.
AmJPhysiol.1931;97:271–275.
11.FriedmanWF,PoolPE,JacobowitzD,Seagren
SC,BraunwaldE.Sympatheticinnervationof
thedevelopingrabbitheart.Biochemicaland
histochemicalcomparisonsoffetal,neonatal,
andadultmyocardium.CircRes.1968;23:25–
32.
12.OkudaH,NakanishiT,NakazawaM,TakaoA.
Effectofisoproterenolonmyocardial
mechanicalfunctionandcyclicAMPcontentin
thefetalrabbit.JMolCellCardiol.
1987;19:151–157.
13.DelgadoC,ArtilesA,GomezAM,VassortG.
Frequency-dependentincreaseincardiacca(2+)