comparedtosingleventricularphysiology..
KwiatkowskiDM,GoldsteinSL,CooperDS,
NelsonDP,MoralesDL.KrawczeskiCD.
Peritonealdialysisvsfurosemideforprevention
offluidoverloadininfantsaftercardiacsurgery:
arandomizedclinicaltrial.JAMAPediatr.
2017;171(4):357–364.
Thisprospectiverandomizedstudycompared
outcomesbetweenpatientsrandomizedto
peritonealdialysisversusfurosemideafterthe
developmentof4hoursofoliguria(UOP
<1mL/kgperhour).Allpatientshadperitoneal
dialysiscathetersplacedintraoperativelybased
onriskstratificationforAKI.Patients
randomizedtoperitonealdialysisexhibited
lowerratesofdelayedextubation,development
of10%fluidoverload,andelectrolyte
derangements..
KakajiwalaA,KimJY,HughesJZ,etal.Lackof
furosemideresponsivenesspredictsacutekidney
injuryininfantsaftercardiacsurgery.Ann
ThoracSurg.2017[Epubaheadofprint].
Thisretrospectivestudyassessedforthresholdsof
diureticresponsivenesstopredictAKI
developmentininfantsaftercardiacsurgery.
LackofachievingUOPof1mL/kgperhourat2
and6hoursaftercardiacsurgerywas
associatedwithsubsequentAKIdevelopment..
BojanM,GioanniS,VouhePR,JournoisD,
PouardP.Earlyinitiationofperitonealdialysis
inneonatesandinfantswithacutekidneyinjury
followingcardiacsurgeryisassociatedwitha
significantdecreaseinmortality.KidneyInt.
2012;82(4):474–481.
Thisretrospectivestudyassessedearly
(postoperativeday1)versuslater(postoperative
day2orlater)peritonealdialysisinitiationand
outcomesininfantswithAKIaftercardiac
surgery.Patientswhoreceivedperitoneal
dialysisearlierhaddecreased30-and90-day
mortality..
MadsenNL,GoldsteinSL,FroslevT,Christiansen
CF,OlsenM.Cardiacsurgeryinpatientswith
congenitalheartdiseaseisassociatedwithacute
kidneyinjuryandtheriskofchronickidney
disease.KidneyInt.2017[Epubaheadofprint].
ThisstudyfromtheDanishNationalHealth
Serviceregistryassessedforanassociation
betweenpostcardiacsurgeryAKI,andchronic
kidneydiseasedevelopment5to15yearsafter
surgery.Patientswithcardiacsurgery–
associatedAKIhada3.8timesincreasedriskof
chronickidneydiseasedevelopment5yearsafter
surgery..
GreenbergJH,ZappitelliM,DevarajanP,etal.
Kidneyoutcomes5yearsafterpediatriccardiac
surgery:theTRIBE-AKIstudy.JAMAPediatr.
2016;170(11):1071–1078.
Thisprospectivemulticenterstudyassessedforan
associationbetweenpostcardiacsurgeryAKI
andchronickidneydiseasedevelopment5years
aftersurgery.Allpatientshadincreasedratesof
hypertension,proteinuria/microalbuminuria,
andglomerularfiltrationratesof<90mL/min
per1.73m2thanahealthypediatricpopulation.
Theratesofthesechronickidneydisease
markersdidnotdifferbetweenpatientswho
experiencedpostcardiacsurgeryAKIandthose
whodidnot..
KrawczeskiCD,GoldsteinSL,WooJG,etal.
Temporalrelationshipandpredictivevalueof
urinaryacutekidneyinjurybiomarkersafter
pediatriccardiopulmonarybypass.JAmColl
Cardiol.2011;58(22):2301–2309.
Thisprospectivestudyisthelargesttoassessfor
theabilityoffournovelurinaryAKIbiomarkers
topredictAKIdevelopmentandseverity.All
biomarkersperformedwellandalthoughthey
appearedatdifferentpostoperativetimepoints,
allwereincreasedinpatientswhodeveloped
AKIpriortoariseinserumcreatinine.In