Pediatric emergency medicine trisk 2363 2363

• Rash: generalized erythematous
macular; may desquamate
• Soft tissue necrosis (necrotizing
fasciitis or myositis, or
gangrene)
ã Renal: BUN or creatinine at least
2ì ULN or pyuria
ã Hepatic: total bilirubin, ALT, or
AST at least 2ì ULN
• Coagulopathy: platelets
<100,000/mm3 or DIC
a Centers

for Disease Control and Prevention Case Definitions, 2010 (Streptococcal) and 2011
(Staphylococcal). Available online at />CondYrID=869&DatePub=1/1/2011 %2012:00:00%20AM. Accessed February 26, 2019.
b Probable cases meet the laboratory criteria and 4/5 clinical criteria; confirmed cases meet the laboratory
criteria and 5/5 clinical criteria.
c Probable cases met the clinical case definition in the absence of another etiology and have GAS isolated
from a nonsterile site; confirmed cases meet the laboratory criteria and have GAS isolated from a sterile
site.
GI, gastrointestinal; CK, creatinine kinase; ULN, upper limit of normal; BUN, blood urea nitrogen; ALT,
alanine aminotransferase; AST, aspartate aminotransferase; CSF, cerebrospinal fluid; TSS, toxic shock
syndrome; RMSF, Rocky Mountain spotted fever; CHF, congestive heart failure; DIC, disseminated
intravascular coagulation; GAS, group A streptococcus.