LIÊN KẾT GIỮA HAI NUCLEOPHILES.

ĐẠI HỌC QUỐC GIA TP.HCM
TRƯỜNG ĐẠI HỌC BÁCH KHOA
KHOA KỸ THUẬT HOÁ HỌC
SEMINAR MÔN HOÁ HỌC CƠ KIM
LIÊN KẾT GIỮA HAI NUCLEOPHILES
Học viên: Lê Minh Đạt
Phạm Thái Hòa
GVHD: TS. Trương Vũ Thanh
1
Nucleophiles
2
Traditional Coupling and oxidative coupling
3
Traditional Coupling
Oxidative coupling
4
Couplings between Two Organometallic Reagents
as Nucleophiles
Csp-M and Csp-M as Nucleophiles
5
Csp-M and Csp
2
-M as Nucleophiles
6
Csp-M and Csp
3
-M as Nucleophiles
7
Csp
2
-M and Csp

2
-M as Nucleophiles
8
Csp
2
-M and Csp
3
-M as Nucleophiles
9
Csp
3
-M and Csp
3
-M as Nucleophiles
10
11
Oxidative Couplings between Hydrocarbons and Organometallic Reagents
Csp-H (Terminal Alkynes) and Organometal
Reagents as Nucleophiles
12
Csp
2
-H (Arenes or Alkenes) and Organometal
Reagents as Nucleophiles
13
Organoboron Reagents
Csp
2
-H (Arenes or Alkenes) and Organometal
Reagents as Nucleophiles

14
Organozinc Reagents
Csp
3
-H (Alkanes) and Organometal Reagents as
Nucleophiles
15
Cyanide Ion
Csp
3
-H (Alkanes) and Organometal Reagents as
Nucleophiles
16
Cyanide Ion
Csp
3
-H (Alkanes) and Organometal Reagents as
Nucleophiles
17
Organoboron Reagents
18
Oxidative Couplings between Two Hydrocarbons
Csp-H and Csp-H as Nucleophiles
19
Csp-H and Csp
2
-H as Nucleophiles
20
Csp-H and Csp
2

-H as Nucleophiles
21
Csp
2
-H and Csp
2
-H as Nucleophiles
22
Couplings between Arenes
Csp
2
-H and Csp
2
-H as Nucleophiles
23
Couplings between Arenes and Alkenes
Csp
2
-H and Csp
3
-H as Nucleophiles
24
Csp
3
-H and Csp
3
-H as Nucleophiles
25