Cardiac drugs 1e (2013) PDF UnitedVRG khotailieu y hoc

CARDIAC
DRUGS



CARDIAC
DRUGS

Editors
Kanu Chatterjee MBBS FRCP (London) FRCP (Edin)
FCCP FACC MACP

Clinical Professor of Medicine
Division of Cardiology
The Carver College of Medicine
University of Iowa
Iowa City, Iowa, USA
Emeritus Professor of Medicine
University of California
San Francisco, California, USA
Eric J Topol MD FACC
Director, Scripps Translational Science Institute
Chief Academic Officer, Scripps Health
Vice Chairman, West Wireless Health Institute
The Gary and Mary West Chair of Innovative Medicine
Professor of Translational Genomics
The Scripps Research Institute
La Jolla, California, USA

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or application of any of the contents of this work. If not specifically stated,
all figures and tables are courtesy of the contributors. Where appropriate,
the readers should consult with a specialist or contact the manufacturer of
the drug or device.
Cardiac Drugs/Editors Kanu Chatterjee, Eric J Topol
First Edition: 2013
ISBN 978-93-5025-879-8
Printed at:


Dedicated to
Our wives
Docey Chatterjee and Susan Topol



CONTENTS

Contributorsix
Prefacexi
Acknowledgmentsxiii

CHAPTER 1

Angiotensin, Aldosterone, and Renin Inhibition in
Cardiovascular Disease

1

Abdallah Kamouh, Gary S Francis, Kanu Chatterjee
CHAPTER 2

Positive Inotropic Drugs: A Limited but Important Role

34

Carl V Leier, Garrie J Haas, Philip F Binkley
CHAPTER 3

Antihypertensive Drugs

72

William J Lawton, Kanu Chatterjee
CHAPTER 4

Diuretics158
Michael E Ernst
CHAPTER 5

Drugs for Dyslipidemias

184

Byron Vandenberg
CHAPTER 6

Drugs for Diabetes and Cardiodysmetabolic Syndrome

242

Prakash Deedwania, Sundararajan Srikanth
CHAPTER 7

Drugs for Acute Coronary Syndromes

267

Stephen W Waldo, Yerem Yeghiazarians, Kanu Chatterjee
CHAPTER 8

Drugs for Dysrhythmia

326

Rakesh Gopinathannair, Brian Olshansky
vii


CARDIAC DRUGS

CHAPTER 9

Drugs for Heart Failure

389

Kanu Chatterjee
CHAPTER 10

Drugs for Stable Angina

424

Kanu Chatterjee, Wassef Karrowni
CHAPTER 11

Drugs for Pulmonary Hypertension

454

Ravinder Kumar, Sif Hansdottir
CHAPTER 12

Cardiac Drugs in Pregnancy and Lactation

485

Wassef Karrowni, Kanu Chatterjee
CHAPTER 13

Future Directions: Role of Genetics in Drug Therapy

506

Eric J Topol

Index509

viii


CONTRIBUTORS

Philip F Binkley MD MPH
Wilson Professor of Medicine
College of Medicine, The Ohio
State University
Professor of Epidemiology
College of Public Health, The
Ohio State University
Vice Chairman for Academic Affairs
Department of Internal Medicine,
The Ohio State University
Director, Center for FAME
Associate Dean for Faculty Affairs
College of Medicine, The Ohio
State University
Columbus, Ohio, USA

Michael E Ernst Pharm D
Professor (Clinical)
Department of Pharmacy

Practice and Science
College of Pharmacy
Department of Family Medicine
Carver College of Medicine
The University of Iowa
Iowa City, Iowa, USA
Gary S Francis MD
Professor of Medicine
Cardiovascular Division
University of Minnesota
Minneapolis, Minnesota, USA

Prakash Deedwania MD FACC
FACP FAHA

Chief of Cardiology Division
VACCHCS/UMC, UCSF Program
at Fresno, Fresno, California, USA
Professor of Medicine
UCSF School of Medicine
San Francisco, California, USA
ix