nghiên cứu hội chứng ngưng thở khi ngủ tại bệnh viện trường đại học y dược huế

506

NGHIÊN CU HI CH KHI NG TI BNH VING
I HC HU

Hoàng Anh Tin
B môn Ni, i hc Hu

 

 nhân có


                


 

khám và tính BMI, ECG, X-

-C,
HDL-
 



h

SUMMARY

STUDY OF SLEEP APNEA SYNDROME IN HUE COLLEGE OF MEDICINE AND

PHARMACY HOSPITAL

Background: Sleep apnea syndrome is the disease of ceasing the breath when sleeping. The
incidence was 5% in the population, more often in female than male. More than 50% of SAS
patient have hypertension, diabetes mellitus, coronary syndrome or even sudden death. In Viet
Nam there were still a few studies about SAS.
Objective: To evaluate the prevalence of SAS in the patient admitted to hospital by snoring
and/or having the evidence suspecting SAS. Also the correlation between AHI and some
parameters
Methods: Clinical data of 46 patients admitted to hospital by snoring and/or having the
evidence suspecting SAS. We evaluate the incidence of cardiovascular risk in the SAS patients.
We also find the correlations between AHI and age, BMI, systolic blood pressure, diasystolic
blood pressure, fasting glucose, Cholesterol, Triglyceride, LDL-C, HDL-C, Epworth scale, neck
curriculum.
Results: 1. Prevalence of SAS in the patient admitted to hospital by snoring and/or having
the evidence suspecting SAS is 65,20%. 2. There were positive correlation between AHI and
systolic blood pressure r=0,37, p<0,05; neck curriculum r= 0,36, p<0,05; Cholesterol r= 0,32,
p<0,05; Epworth scale r= 0,48, p<0,01; BMI r=0,41, p<0,05.
Conclusions: Basing on the correlation, cardiovascular risk should be concerned in SAS.



   
507
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
2
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



[27].

[24]


[19].






               
Cholesterol, Triglyceride, LDL-C, HDL-





Nghiên cu mô t ct ngang

Bnh nhân tr li mt bng câu h bun ng m
Epworth và  li m c ng bc).

i khoa Ni Tim mi hc Hu
B sng, BMI, vòng b
h, khám tim mch, khám thn kinh, ni tit [25].

- -

- -
- [15],[27]

[9]



508



 



.








2.1. 

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









2.1. [3]

h nhân ngày to



vào ban ngày
Có
Không
Không

Có
509
III. 

Hình 2. 


Bng 3.1. m ca nhóm bnh nhân có HCNTKN và không có HCNTKN


(n=16)
HCNTKN
(n=30)
p

46,67±12,48
49,26 ±11,32
>0,05

Nam
9 (56,25%)
19 (63,33%)
>0,05

7 (43,75%)
11 (36,67%)
>0,05
BMI (kg/m
2
)
19,87 ± 2,99
23,03 ± 4,53
<0,05

(cm)
Nam
41,89 ± 15,72

43,56 ± 12,63
>0,05

36,43 ± 11,65
40,84 ± 14,21
>0,05

80,17 ± 8,18
87,16 ± 11,12
<0,05

130,53 ± 26,14
149,03 ± 28,98
<0,05

71,58 ± 15,62
81,67 ± 9,83
<0,05
Glucose (mmol/l)
6,43 ± 1,78
7,20 ± 1,34
>0,05
Cholesterol (mmol/l)
4,93 ± 0,90
5,28 ± 0,83
>0,05
EF (%)
63,46 ±11,93
58,11 ± 13,45
>0,05

FS (%)
37,92 ±8,27
33,54 ±9,66
>0,05
510
3.2. 


(n=16)
HCNTKN
(n=30)
p

3,45 ±1,38
8,34 ± 3,37
<0,01
AHI
3,87 ± 0,63
27,66 ± 11,51
<0,001

4,26 ± 0,43
34,67 ± 12,43
<0,001

3,64 ± 0,57
25,90 ± 11,48
<0,001
SpO2 (%)
97,67 ± 0,82

95,05 ± 1,39
<0,001

0,61± 0,23
11,32 ±2,96
<0,001
u
0,78± 0,19
22,17 ±5,73
<0,001
3.3. 

5-14
15-29

BMI
20,27± 4,38
21,59 ± 4,49
22,03± 6,52

39,34 ±13,86
38,16± 12,86
40,76± 14,92
SpO2 (%)
95,67± 2,52
95,57± 0,79
94,44± 1,24

89,11 ±9,08
81,86 ±14,09

93,67 ±3,06
HATT (mmHg)
124,29± 20,82
126,67± 26,37
156,67 ±24,49
HATTr (mmHg)
81,67±9,83
78,89 ±15,37
87,65 ± 11,75
Glucose (mmol/l)
5,32 ± 0,99
6,05 ±1,74
7,33 ±2,19
Triglycerid(mmol/l)
1,77± 0,43
2,00± 0,57
2,31± 1,27
Cholesterol(mmol/l)
5,53± 0,41
5,50 ± 1,18
5,02± 0,56
HDL-Cholesterol(mmol/l)
1,35± 0,62
1,06 ±0,29
1,17± 0,17
LDL-Cholesterol(mmol/l)
2,82± 0,64
2,80± 0,60
2,95± 1,10


g 3.4. 

n
%

16
27,59

11
18,97
Béo phì
12
20,69

8
13,79

5
8,62

6
10,34
p
<0,001



3.5. 



r
p
HATT (mmHg)
0,37
<0,05

0,36
<0,05
Cholesterol (mmol/l)
0,32
<0,05

0,48
<0,01
BMI (kg/m
2
)
0,41
<0,05



511


3.1. 






  
Leticia Boari [11]



- 
[27]


[11].

[5],[6]

[28].


[20]
[28]


 [1] 
 [12].




r
p
HATT (mmHg)

0,37
<0,05

0,36
<0,05
Cholesterol (mmol/l)
0,32
<0,05

0,48
<0,01
BMI (kg/m
2
)
0,41
<0,05

[13],[16]   [7],[18],[26] ipid
[8],[10],[32]
512
               
               

[22].

 [31]

[14],[17],[21] [23],[30].
Theo Gami 
[4].Theo Yaggi 

 
[29]. Theo Baguet JP [2]





                  






             
r=0,41, p<0,05.


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