570
NG MCH CNH I CAO TUI
Nguyễn Hải Thuỷ
.
Mục tiêu:
Đối tượng và phương pháp nghiên cứu:
Kết quả:
27,59% và bên trái là 30,0
MMN là 68
Kết luận:
SUMMARY
Objective: To study the atherosclerotic lesions of carotid artery by measuring the intima
media thickness (IMT), plaque of atherosclerosis and resistance indice (RI) in the patients over
the age of 60 years by using the carotid doppler ultrasonography
Patients and methods: A cross-sectional analysis was conducted among 243 patients
hospitalized at internal medicine department in Hue university hospital. These patients were
divided in 2 groups including (1) group of 40 patients under the age of 60 years and (2) study
group of 203 patients over the age of 60 years
Results: The average of IMT of the left common carotid artery was 1,08 ± 0,47 mm thicker
than that of right CCA (1,03 ± 0,45 mm).The frequence of carotid atherosclerosis was 60,59% of
patients, the average thickness of atherosclerotic plaque was 2,58
1,12 mm, in which the
thickest was 6 mm and the smallest was 0,8 mm.
The prevalence of atherosclerotic plaque in the right CA was 49,25% and in the left CA was
53,69%, in the right bifurcation was 27,59% and the left bifurcation was 30,05%, in the right
CCA was 11,33% and the left CCA was 10,34%, in the right internal CA was 34% and the left
ICA was 13,3% of patients .The average RI of right CA was 0,68 ± 0,07 cm/s and the left CA
was 0,67 ± 0,08 cm/s in the normal value.
of atherosclerotic carotid was 57,29% of stade 0 and 65,79% of stade 3. The carotid IMT in stade
1 were 1,08 ± 0,53 mm and 1,21± 0,55 mm of stade 3.
The thickness of atherosclerotic carotid in stade 0 were 2,34 ± 0,79 mm and 2,32 ± 1,25
mm of stade 3. The prevalence of atherosclerotic carotid in patients with stroke was 63,55%
571
higher than that of non-stroke (57,29%). The carotid IMT in group with stroke was 1,22± 0,55
mm thicker than that of non-Stroke (0,96± 0,30 mm) and the thickness of carotid plaque in group
with stroke 3,00± 1,19 thicker than that of non-stroke (2,07± 0,78 mm).
Conclusions: Athersclerotic carotid lesions (IMT, plaque and RI) in patients over the age of
60 years presented remarcable and could be determined by doppler ultrasonography
Carotid doppler echography revealed atherosclerotic lesions in patient without symtomtology of
cerebral vascular hemodynamic dysfunction (stade 0 of Natali Thevenet clinical classification)
Hoa
qua. Trên
.
g
iêu âm
.
ng nghiên cu gm 243 bi ln nhp vin ti Khoa Ni thuc Bnh
ving i Hc Y Khoa Hu. Các bnh nhân trong nghiên cc chia làm 2 nhóm
Nhóm chi 60 tui
Nhóm nghiên cu trên 60 tui
u ct ngang, mô t i chng
Tt c bnh nhân nghiên cng mch cnh
oli. và cng s
Bên trái
IMT (mm) (n = 203)
1,03 ± 0,45
1,08 ± 0,47
572
Bên trái
n
%
n
%
n
%
ÐMCa chung
23
11,33
20
10,34
12
5,91
Ch chia dôi
56
27,59
58
30,05
41
20,20
ÐMC trong
21
10,34
26
13,30
14
6,90
T
100
49,25
109
53,69
67
33,0
.
89 (72,36)
7
< 2mm
34 (27,64)
0,8
Trung bình (mm)
2,58 ± 1,12
1,12
Bên trái (cm/s)
RI
0,68 ± 0,07
0,67 ± 0,08
,08 cm/s
n
%
0
96
47,29
1
4
1,97
2
27
13,30
3
76
37,44
203
100,00
XVÐM (%)
n
%
0 (n =96)
55
57,29
1 (n=4)
2
50,00
2 (n=27)
16
59,26
3 (n=76)
50
65,79
n=203
123
60,59
IMT
XVÐM
RI (cm/s)
X ± SD
X ± SD
X ± SD
0 (55/96)
0,97 ± 0,34
2,07 ± 0,78
0,69 ± 0,67
1 (2/4)
0,90 ± 0,14
2,40 ± 0,85
0,73 ± 0,04
2 (16/27)
1,18 ± 0,40
3,04 ± 1,56
0,74 ± 0,06
3 (50/76)
1,25 ± 0,60
3,01 ± 1,08
0,71 ± 0,08
573
TBMMN
n
%
TBMMN (n = 107)
68
63,55
Non - TBMMN (n = 96)
55
57,29
TBMMN (57,29%)
TBMMN
IMT (mm)
XVÐM (mm)
RI (cm/s)
TBMMN
1,22 ± 0,55
3,00 ± 1,19
0,72 ± 0,07
Non - TBMMN
0,96 ± 0,30
2,07 ± 0,78
0,69 ± 0,07
p
< 0,01
< 0,01
> 0,05
Bề dày lớp nội trung mạc (IMT) của động mạch cảnh
là: 0,729
0,02mm.
0,08mm
0,11mm
là 0,98
0,03mm
Arno Schmidt - Trucksass v
dày IMT trung bình: 0,55
0,06
0,27mm.
0,84
0,27mm.
Mảng xơ vữa động mạch
Lê N
1,82% .
574
M
%
%, bên trái là 13,3%
p bên trái là 57,1% .
-
p > 0-2mm
TBMMN
g 0,6-
MIT (
Qua siêu â
là 2 (50%), g
575
mm, giai
h nhân không TBMMN chúng
TBMMN là 55 (57,29%).
và
nhóm không TBMMN là 2,07±0,78 mm.
là 0,72± 0,07 và nhóm không TBMMN là 0,69 ± 0,07.
Georg
-1,11 mm) dày
-0,91 mm).
Qua
TÀI LIU THAM KHO
1.
Kỷ yếu toàn văn các công trình nghiên cứu
khoa học -925
2. Nghiên cứu tổn thương thành động mạch cảnh và động mạch
hai chi dưới ở bệnh nhân đái tháo đường không phụ thuộc insulin bằng siêu âm để phát
hiện sớm các thương tổn xơ vữa động mạch
3. Daniel H, O leary, Joseph F.Polak (1995), Thickning of the carotid wall, A marker for
atherosclerosis in the elderly, Medline.
4. Georgios Tsivgoulis, Konstantinos Vemmos, Christos Papamichael (2006), Common
carotid artery intima media thickness and the risk of stroke recurrence. Stroke.
5. Laura L.Schott, Rachel P. Wildman, Sarah Brockwell. (2004). Segment-specific effects
of carotid vascular risk factors on carotid artery intima medial thickness in women at
Midlife. Arterioscerosis, Thrombosis, and vascular biology. 24:1951- 1956
6.
media thickness as a risk factor for myocardial infarction and stroke in older adults. N
Engl J Med, 340(1): 14-22
7. P.Poredos (2002). Carotid intima media thickness- indicator of cardiovascular risk. E.
Journal of cardiology pratice. 1(13).
8. Trucksass AS., Sandrock M. (2003), Quantitative measurement of carotid intima-media
roughness - effects of age and manifest coromary artery disease, Atherosclerosis, p. 57-64.