Đánh giá tình hình cảm nhiễm virut newcastle bằng phương pháp SSIA ở gà giết mổ và gà tại các vùng nuôi khác nhau

DANH MỤC CÁC TỪ VIẾT TẮT

 ! "#
$$%&' ()
! "
$$%&' ()
$$*%&'+, ()
-/.*
%01%01
2-%32-"/04567 89:;
*<=8>
?@?@?A;*BC
1D*
E2E2F'G4 H
DIJDKL*&
$0/MD$()/M!
MỤC LỤC



 !"#$"%&'(&)*+
,- !")*+
.,-/0(123"-)*4
5$(67&89:"6;"(67"8.
<0"="&>$?"8"$")+*.
@99%&'(&)*
AB:8CB69DB)*
..EFGH" 9 IC9""J"-".+
58BKL(;5(M"(MCINI  0OPI>I(M$KQRSKL(
C5T6"E.
U

U
FGH" 9 T(1$(E
VWAXYZ[%@\V]%O^ZW_\[`Za%E+
EQQ>9 P"b:$"(7%&'(&>8;\IE+
DANH MỤC CÁC BẢNG



 !"#$"%&'(&)*+
,- !")*+
.,-/0(123"-)*4
5$(67&89:"6;"(67"8.
<0"="&>$?"8"$")+*.
@99%&'(&)*
AB:8CB69DB)*
..EFGH" 9 IC9""J"-".+
58BKL(;5(M"(MCINI  0OPI>I(M$KQRSKL(
C5T6"E.
U
U
FGH" 9 T(1$(E
VWAXYZ[%@\V]%O^ZW_\[`Za%E+
EQQ>9 P"b:$"(7%&'(&>8;\IE+
I. ĐẶT VẤN ĐỀ
0+G =8;A5N9 H3
OPGQGH+GK8KO9+G
*R8"!QOK)BS+GTU"GA
VP+;*O 3 7!*,K B*
DWXYOZNK*K[CKKK=*S
&3<CK*9\L"AC8K=]^_`X

SU"KX8;XXa]bc`3JOZ"!8K+dec_
:Of"C>"OZ=F;KRK"7DWXOQg
4Of"!*SN*KK*DW]ch`3
J=R8=88XNParamyxoviridae,]^_`K=
1D8XP8iX8KPOUAC (),KXSX*Y8K8;
GC ()jXkX8Ki]^l`
<Z"!8KV+clm gclXO 8
O9;*8nR 5&Km 8nK!"o!*
"!""YKA3JOK8LO9NK)XP&
,HO  +G=OB8K+GKG"3
JPU"4 H]cc`XK=fLK,C
pXC%8KJ@q3J,0CpX0C%SU4Y,J
@qS,Qr3sPAO=j3gt8)dlluP
Q&OK)OZ8+3 sTPQC
\8KCt8&OK )OfOZ"Y]cd`3
J&,N'FXSv"8H9*!,)8KC
g Heldll%]c`3DVF*8KR;O;"4
SC!R8KFLN9 57CX
PQO KOG w18K.8Xdeehx ]cy`3 JDW
OZ#O!)O),+dez_8KOf &zl/ylu7
K,K5a+3 {<K.k!c/z|deyb*Of&,
cbzRKdd8[8HcX_hK*8KlXz_ ]z^`3
{D"X*DWC &zuF7K3;@q;*
+cllc/cll^nO ! m4*)8KKG
"GKRHA,'zg}:]cl`3{H+deyhR
K%~;X<GX$KD=*DWOfH"Ozh3lllKX
deybdeyzRCD'o%4=s0+DGOf
 8Kmdy3lllK!R]de`3*!!m0o~•==
&F'RK%7$(0A@8K+deebX 5&O9*
DW+deeddeecLg*^lu8Kg

 kdz/cluXP€RO b/zgO(]b`37m%Y
Mq>,DG.CD"$KD=BF7K *DW
k+dee^deez dbdhu]bd`30A8B'O=Qm*
K*OfOZF';\ Hw2-x "8Ko*&!
*9\Q,8>G8KK***="&G*7
P;]yc`3
$[8Hj\* "'R"X'O=QT
"R8&,m~)K*DWSO*;
f538>X8HVFLK*DWC9
 B*8n8KOYKOO)!K5&•;*3@U[X
€k$ OfK7G!5RYFT!"o
9*"!"8"Y*,!R+GX!=OB
8H\* "'R"m*B*8nQ7
OZ  8K  4 *[  "!  ;      =  K  L  H3 :  OPX  *
DW8n8KOKO7Z~•m9KG3D9
*"!""Y*OfOZ'87 *8n
OR5&3
sB8>8!O;BB&\8DW8K4
*["!*K=8KLP•‚Xƒ~"K„jR\
)*DW,K=!O;*KG!T
'XO!!&+7R*mKGG=XkOPPQK
S+GTO=T5&•~•LOZjR
)*RO;"4XƒP"")Gi8O9!
*"!""YX7 ;*8KOVO9L5O 
8to8TO!!895B8+"Y7
*K3IL"!k)j\OP8K))P="4
"!"#O!*8K5&X~GjO9K“Đánh
giá tình hình cảm nhiễm virut Newcastle bằng phương pháp SSIA ở gà giết mổ
và gà tại các vùng nuôi khác nhau trên địa bàn Thành phố Huế”.
1.2 Mục tiêu

<!!BB\;7R*DWOKK,O;
*KK%7$ XkOPO!!&+! kKK
(!Q#"&' ()
! "wx[8H()!8*DWk
8.OU3
to! K F>"OZ"&'v
"!*DWw$xOQ!O;BBK)
*DWOKK,!8[G!mK%7$ 3
I!O;gK!DWRYFX8[C>
8K8["o>!YF^*…"4"!"3
! 5&"!!X!Q8DW,!
8[G!O;*KK%7$ Xj8K"&'8K
"&'$3
!gK)*DW,!SOQ!3
1.3 Ý nghĩa khoa học và thực tiễn
1.3.1 Ý nghĩa khoa học
M 5&'P"")K„jR\*DW
mK,YFX8[C>8K"o>!YF^O;*KK
%7$ 3
M 5&T7KS+GTO=T
5&•~L„jR)*DW8K&+O9
!mOKKGR!8[O;*K!34,OP~"
S+GP•'G!+PXG†X8~8K
"Y!*DWK=!5&3
1.3.2 Ý nghĩa thực tiễn
M 5&89jK8C*DWOKKGL
5N8O!*"!""Y7X7 8K H
!;*QK3
<9KO"4"!"#O!X‡98KP8H
ˆPOQ#O!*3

II. TỔNG QUAN CÁC VẤN ĐỀ NGHIÊN CỨU
2.1 Lịch sử bệnh và địa dư địa lý
2.1.1 Lịch sử bệnh
.;tD+dech*OZ"!O),O&‰83D+dy^^
%)O)OfG&89=>;&K,$3< +dyylX
:",Š*O)"C*;&K8H*o [K8KN
KTyphus exudativus gallinarum3D+deldXIB*K=R
83kOPS8;&KK+*L3sK+dech
M8>d>;&K,5)O&‰8,3OP+
dec_,RGK"7DWHR"!L=7F;
&KFOQX' NRL+*POUA
KK!3:;*,&Kv"P5O 
=K8>Q;OGRKGQk0Cp
O &DW]bb`3
D+dec_X:Of"C>"OZ)*F;KRK"7
DW8KTKSO)'8"C>"OZPA!
!8H8;&K3<Qg4"!*KSOf
N*KDW;&K0Cp]^z`30Y*;&KOZ
BLHNK*;&KFOQX;&K0C‹;&K
>]ch`3DK*;&KOZ!O;K~)]^l`3
2.1.2 Địa dư bệnh lý
JP,"4 HK=fLK,0C
pX0C%8KJ@q3{0CpX0C"*SU4]ch`3
{sD*OZ>k+debeX*9L
8KCRHO78HKGG"TKGOB3
2.2 Giới thiệu chung về viruts gây bệnh Newcastle
2.2.1 Đặc điểm hình thái, tính trạng lý hóa của viruts
sDWK%@s/d(Paramyxovirus-1xX=RubulavirusX=
ParamyxovirinaeXN Paramyxoviridae]^l`3<CK81DP!K3M
5!HAQ8OtLsPOSAdzl/^ll

4!Orthomyxovirus~AX~SPRB)XB5U
BZ3pKPO=K&dl*9UPRw"x
"" "Uƒ3:G*98V*;KOG!
OZ B8i*NKS*;"!mL\KX8>H
AQ8OtSL")3D"O7'
RZkP9=db/dyX9K&dŒ]^l`3sP
Q5OZ7NJX0*8KKN]^b`3H
OCSS)n*DW8H*;&KX8B&R
8KO9PQC ()mKXSX*YX8;X=X
=*R3DKSOfPQ"C*\K~KS
8DWGC ()jXkXXi8;
&K]^l`3
2.2.2. Cấu trúc của viruts Newcastle
$m8DWKaO41DOQ9G8K>
f9K!"m83sPNZ"Ct1DUzXc/
zX_dl
h
L"€dz*wM*xwMXde_bx]zc`8K 
lXzuNZ8.$…7&zl/z_]cy`3
sP_/y"fw21E2"/ON
,KOR:DOmKXG*;U*,*=*fkOQfP=
"""'+"xXOP9%OZf[U"Pj
(U"PQ";OZdl/dcR"3
sDWP_R"L~$/D
w$DxXE"wExX."w.xX@"w@xXD"
wDxX%$ ]^l`X %""wD%x]^z`3
0'+mkR%L~
 D"wDx.K="9 Z"8H1DRK
"P!o*&81Dm83
 $/Dw$Dx0POUA ()

8KPRAmDP!oO'!oQ()3
 E"wEX"EX"Z"x0PRA
Z"K *K8KRA 3%EOZFZ",R
9Qw"E6xXH!om-"C&"m *K•
mK"CK")KEd8KEc*QRAZ"K
8KPRO=5N8C>"m88KBK!
*KF(OC3
 %$w"*"";mx„
'+X…VE8K$D3
 .  "  w.x  0P  "C  t  Z  H  LX    R  A
"8KK"K")"'Z"QPRAf3
 @"w@X"K"9x(RU
!KXP!o1D88H8i*N3
 %""wD%x$B7K8K798Y
„'+3
7V"KXPc"8KRO=m
8X8KP5O 8i*N"OPK$"C
 ()XDO'oQ()8KE"C
 ! *K*;\8K *KOCF(3DV"
KP5O RO=m8O78H *K8K&+K
!Q3
2.2.3. Tái sản
Paramyxovirus  Z"8HoQP'BSR
AZ"Km"EKCZ"!K8HK *KX
O"8K* *K3"OfPˆ
1D/""o=1DXH!omKG
1D8\jFZ"!1DO4w1D"€=
L~xPO=K!3"X!1DPF
Z"!R"m83<(S8H5!BOPX1D8\
5!BFZ"KKOQBKa1D4XG

a4K1D8waCxOZFZ"8K Z"8H
"L~8kOZFZ"KBK"3@=U!
"8kOZFZ"OZQkRH=LˆX(*=
!?8KO K *KLKFZ"8KK *K3
%@OZFZ"4jTO=HK *KL
8K7O;8H!",K3D"O=O H"
@X>!KS&(5KOf* OFˆKKo3
DKj !&\!&(5K
YO(S\B'9k *K5 *K3MOPXS4
+Z"Km"EXLjZ",*9U *KX5
OPk *KOf&\1D8>"! *KC>3sB8>X
BK! *KF(OU3<(SX&\vKTK
OU!m!8=NK]^l`3
2.2.4 Các chủng và chỉ số độc lực của từng chủng viruts Newcastle
sDWP9mX!mKPO=j!X
+'8KAO=8K&+C*SKbP
 DPs?(!mPO=jXOPAK8
SO=jYNK8DWOS"73
 DP@?(!mPO=j8kXKV8€
C*rKh)Fm$w$x•m@
w@WxXmK"GKdl/ddKXK "G
8KL K"G3
 DP..K! mPO=jL"(V8
GP&+C*U€C*rKH,XP
&+\;7mJdXm.XmE3
 DP8OfOZH8K*(!mGC
*w"*WX%JXdey_x3
"YAX!mOZPRgt8"G
K3sKOZO*…S *Bw@:xm"GOZL8H
8*…OSw=~x3

Bảng 2.1. Chỉ định độc lực của vi rút bệnh Newcastle [5]
Chỉ Độc tính ở gà Khoảng MDT
Velogenic
0mO=jXOQ  =g
")+mK
Ž4hlS
Mesogenic
 0m  O=  j  8k  XC  *  
NX=7) 8K &&
Z'
khlO elS

Lentogenic
0mO=jL"C*GL"OU
*K,K8K&&Z'3
$4elS
Avirulent MGC* MG  "G
0~A
/@:KS*B9C 7QOQ"G
OZ"Y3
s!O; O= j m  !m8 DW  *… !  t
!O;@:X0%Xs%5Bm2-wclllx8KOZA
'"[Z"8HK&sD]bd`3
Bảng 2.2. Chỉ số độc lực của một số chủng virus Newcastle [46].
Chủng virus Nhóm ICPI IVPI MDT
}c0 . lXl lXl •dzl
6sb . lXl lXl •dzl
$Jd . lXc lXl dcl
E . lXcz lXl dde
. . lXb lXl dl^

$ @ dXc lXl by
@W @ dXb lXl bh
1 @ dXbz lXl hy
J0 @ dXh dXbz hc
?J s dX_z cX_ zz
D•%_ldydde_c s dXy cXy zd
 s dXyz cXy zl
@ s dXe cXy zl
$•^^|zh s cXl cX_ by
%|-|zhd|y^ dXz lXl dcl
0|-|_lc|yb dXe cXd hl
Chú thích
0%w*%x0€7C*8K
fKldKF
s%w8%x0€7C*8K
‚RKlh)F3
@:w@:xS*BC "G
2.2.5 Các thể bệnh do viruts gây ra
:j8KOUAN8KOUOQC*mamXK
*DWOZKzQ*!wJ$X
deyb) ]b_`3
2.2.5.1 Thể Doyle hay thể độc cao hướng nội quan (Viscerotropic
Velogenic)
Q:KQOZ:>O)8K+dec_XC*,
ms3J,QL"AXP€ kel/dlluX&,N
'FX*AOUKL OS!3
2.2.5.2 Thể Beach hay thể độc cao hướng thần kinh (Neurotropic
Velogenic)
<CKQ*OZJ\&8K+debcXC*,m
s3J,QL"AXC ,KN'FXC*A,

GL"8K)KGC*A,!3Q*K
OZNK*GL")U""3
2.2.5.3 Beaudette hay thể độc vừa (Mesogenic)
.KQ*OZJG&8K+debyX**QGL"
L"AXC')O78H)8KC XA
C O78H),K3sCQ*K=m
@XOPPQ[OQ 83
2.2.5.4 Thể Hitchner hay thể phổi (Respiratory)
Q$KQ*C*,8P.mJdX
EX.3Q*OZ$\&+deby3JrG*Q
„'GL"3
2.2.5.5 Thể nội tạng hay thể ruột không triệu chứng (Asymptomatic
enteric)
Q\OS!GP'CK3sPQ
"C>"k"CXRKK*wE8K=jXdeh_x]zl`3<CKm
PO=jL"./c0XsbXPQ[OQ 83
2.2.6 Tính gây bệnh
c3c3h3d Trong tự nhiên
sDWC*!KKXKCXK8K) !
K3?K,'FKTPQ*9LKK
kc/z!F3
s;XXaO9P&+\*DW,'O=
r4XPLAUGPLm*U[m8C 
,K3{a8K8;*P*QCX!8KGP
'GL"3g\ma8K8;&dluUA43g
 ,8;8Ka€&dlu3
DSTPQ*;\8DWXC8 RXOG
P7X'O)8K8T7*;~]e`3 D\$VD
]cb`3BVS\[DWS*;8 R3=
S*kdO bKX8 RL8KS€P

=*3zluSZ"LR5"&'3s
 RvK^/zKXAcO ^)\8Ki‘30TPS
Z"*;\[KCXv78K=='~PUG
P8 R3DVSZ"KL 3s RK'
"F* 3DS*DW "~8HK*U! "
*VooA83sOZO*…*#
UGA3D8>VS\*KVGCGK
G"XGCFK,Y!~X!q>8K8
,!"Yv*)X!q0+G8K*!‚~K
8,!RKG"3
@=7O=8>P8~PX=’T*K]h`3
2.2.6.2 Trong phòng thí nghiệm
JKKe/dlKAL8H8GL83
^h/bySK*=*K8KH''8]ch`3:[KY
OQC*X98KƒP'8K*A7
K*j30PQ[*(CC**…!8
8K*";Xh/yK*(C*;8K dz/dhK3DK
TPQ8KP"~R=X=*R‡ ^/
hK]^z`3
2.2.7 Sức đề kháng của viruts
sDW(Rj"o=8K9 7G
SXO=XPLX8K!O=m*'R3@'O=*98Vm
8DWPQ!O;OZ4,OF&+C\
8X ()8KOUA\;]^z`3sDWPQ
7P8K)GS#HXX"C*P8K!8>
!3
/ DPPQ(R8GSR8>OGR
/ H7P(RO=jdhzK3
/ H'LO""PO="$_XcP(RO=j
^clK3

/ {O=R87C;XOU*)
48Km7X&+C*m8(Rkd^b/dylK]dz`3
/ ;7VX"C8K! mq8G(R5!cbS3
/ F48K9(#H8*;]ch`
/ {O="Y8LRA^K]cz`3
/ {d/b
l
8OZ*&5&AL^/h!3{cl
l0
(RALd+3
:8PK*NKK"8Ln&8K\K*;
"!m*,!L![EduXD2$cuX0cuXV8G
dluXMzuXXX(X%3sK!!C8>•
jA’
/{O=zh
l
08*;^S3
/{O=hl
l
0K^l"~3
/{O=hz
l
0Kz"~3
/{O=dll
l
0Kd"~3
/s*;"!m*,!jA!!US
/:;zluPQV8*"#OZ_K
,^_
l

0]dz`3
2.2.8 Đặc tính nuôi cấy
2.2.8.1 Nuôi cấy trên phôi gà
0L8DW8KGm"GKL"dl/dcKX
[O=jmkm8K"GPQ by/ehSX
P!mPO=j8K8kC "G8YhlSXY
!mPO=jL""&dllSHC "G3JA
"Gm KL OQ,O)8K!Po!8KL "
"G3%GKB&+C\8KS "G
4Xg "GT4]^z`3
2.2.8.2 Nuôi cấy trên môi trường tế bào
0PQGL8DW8KGS *K>ZX>€
U *K"GK=H"Xcb/_cSC\X8KRt
*KXK *K* OFB!X *KYRU8†UR
K! *KF(]^z`3
2.2.8.3 Nuôi cấy trên động vật thí nghiệm
0PQ[KYOQ9GLX8ƒ"!Q8KC
*K7K*j]^z`3
98SO=9OS5f=OQK&
O=jm8X* PKZO=OQ R8+]cb`3
2.2.9 Phân lập virus (chất chứa virus)
sDWPQOZ"C>"k"CXHfXm4X"FX
fX!!XXCX7n'mK*3HfX8PO=
jLR3DSTBL8'8K'm
VK!O‡*;*DW]cb`3
Phương thức lây lan và truyền bệnh
:8>"#)kVH*;\*H
P)*3
jm!KROf\*8[
\*3

:>"OKH8KOKTK=OKOfPOK*;
\*3
: FK*X*!RK7XK*,Z89+K*
CP3
!YFB8 "&VOKK\*O,
S“*P8YOU*Q8BPQ9+*OL3
DKTPQKC\k8Of\)*P
O=jRw)*K\kKr'8K"GXV'
KO 8X8B8>X8OfP)*O=jRx3
JDWSCm *…"4'! "
OSP3DK*YCj "kK*Ki
OSR8K]ch`3
.C\5oo8KS+GOf\* ]d`
{KG"XOS9Cm KOSGL"wTXx
8KRwJ8K$Xdeybx]b_`3sDW~ROS
GL"mK&\X"!*X8OZ&K54,m
K8KGAX8B8>KSQGL"wJ8K-Xdeh_x
]be`XKP'8K4*CK
2.5 Tuổi và mùa vụ mắc bệnh
2.5.1 Tuổi mắc bệnh
?K,L&N'FO9*KH,8KK
,K*r43?Kkc/^)F,OLn&8H*
8BOf &+\;kYOi]h`3?Kn&4K,
KXK,K'O=n&&)3FK+A&
oK&3
2.5.2 Mùa vụ mắc bệnh
@[8oXS PRT&,O 'O=\*X
*DW#m 8K[R8KP9H&[
PjXKPO!"'\;7O78HK[878K8o”
48K8oOGC]_`3?KS*K8K[RXV

8[#L"S*;U]h`3
2.6 Cơ chế sinh bệnh
GS+*OSPOQC>"8K4Q3
sSC\5R)XN(8K!3sC 
\[30TSOP+*O8K) !45F
'm4Q8KC8Rt3D=GK 5&*;"!RC
L 8K#;L8K!4Q3sGj
 "C8"F*)S*;P,N3
DCK8!O=C7R)K8KGL"
m)43
%)HK\*S ,S“\[ 3<PK
QL"A3SZ"*vK4XS,OR7;U
*,VKA&om)3sƒ* Li!(O 
!45"mROQ8K•F')43M 
5&nO Q*RA3%&'78TK=
R!mQ*K]ch`3
s8K4QOZCXCF4jQ *K(
*;&5K8KOZ"!"C8KK'^/z\
*]^h`3
2.6 Miễn dịch chống virus
<78H8C*DWX8K4QKƒAA
O!" '  \  ;        *K  8K  \  ; ;  Qw   
:3‰3Xdee_3s‰•Xclllx]c^`X!!&TOf
€…O!"'\;;QKm 8K!O!"'\;K
P!O=aZnOQ)*3
2.7 Miễn dịch trung gian tế bào
<CKO!"'\;*O)PQ"!c/^KC
\*…!m8873<9KLj*&=,K
L!HXH!!Q!OZ"!]bz`36
j=7!&Of>L8KSZ"[!

!Q'  ()*…GXK8nG 
GSO=]dl`3
X*…!t•"GK*,""OQKL
*K\;8KNNVYKPO!"'\; *K
GPO!"'\;Q;Of'OZ…\;
 *KGP!o78DWGSO=8Hm
?Jw18K@5Xclllx]zb`3
2.6.1.Miễn dịch dịch thể
@\  ;  K  OP  8  Y  5   O;    8  7  R  *
DW3 jBK!Q'  K!Qj "
7R!*9Uw?"$D/ExPQK8
DWw1Xdeyyx]zz`3M!QSL8KK'b/z
*;AA*,!8jU83@'O=
!Q"o=")H8Km8Of\3M!Q+)X
L8K)^/bXOPG+V3
D G>OZAARm!B!Q
!ƒ&)w"*WXdey_x]zh`3M!QPQ(R!
&=+,)OfOZ("oXUR\;8H
8304QOZ!\XO!"'\;)'&R8K
4)O)wXde_yx]b^`3<S\P&,O O!"
'\;X87GOZ!QO(O98K
wXde_yx]b^`3
–Miễn dịch thụ động:D\$(wdey^x]y`
c
c :c

mT
f!XG[!!4X
tt,
')O)8KF*;

rX„7XK
?KG,OZ*…T"&!
(84FK,
$)     ezu  K    ,    k  V  OK *7  r  OZ    "Y
DWO9P!Q\;oO=3M!QKL"8K&
FK3$Dwde__x]zd`!Q,r7
*DWOZ9OS5~YOiXO8K!5!
B"!Qm"G3@'O=!Q,KdKFP5
j "8HKZ!Qmr3$KZ!QoO=
UL"!,KdKFP•‚5NO78HK
)\O)3M!QoO=&)O )'bB)
G"!OZV3:8>X,KH,jPUm!Qo
O=€~"8>O9!8H*=S3<QO&
*&R!\;oK)"&to8+OQR\
;mO=]dh`3sB8>X8Q!QoO=mKK)
 OQ!O;SOQm8)O)3
2.9 Đặc điểm lâm sàng và bệnh tích
2.9.1 Triệu chứng
M*;*DWKSP!'89GL"X)X
P ]db`3?K*SQOm^R'QX[
k!QKQ'PQ 89GL"XP)
3?Kd/c!F*;*U,OSP8K b/_K3
?K,K*;*SQ')3@=7AK
i*')7&OSwrFXOR>"
Qx3JS Q*QAQ5!L"XQL"8KQ
RA3
Q5!L"S€LO)F;3J QXKm
T8KS( XGQ'm*3
QL"AKQ*"F* 3OKKL=7mTX
vRO=X*i+XG[!!43?KO'okPX

KH!OKX#4XK7G!XK!kO‡3D9(P
9*f"CUPH"CYXKG8&i]e`3
Bảng 2.3. Tóm tắt triệu chứng bệnh Newcastle ở thể cấp tính
Triệu chứng Biểu hiện
KC —TX!˜!4™K!&O‡XK7!
DO= 7bc/b^š0
$GL" MP,X˜!!™
P
}79HX'+,9G
/&"CXn!KOin3
g  0_l/elu
wD\s+$KXdey^x]h`
?K*S7bc/b^š03P!'O)X
K*;&R(),P,)N3kT=LHK
!XOiRX4H&3?K*4GXSK
 ˜!!™OQ\,3JUKG,OZ*…T"&!
(84FK,3DH*NXHn*N&3D QPQ
LK&*K!n,RX)8KN]_`. ?K*
*;7RP30~*i+X7H93'+,9GX
f3M)C7ZXk(ƒ&LS[
3JvK8KKK€&3%C~O)YOUX
f)K CnX!3.GOG* O)"C3
@K K*;A*)S“P,3K!)L!3
QKKS 8KK*R 3g LP
O dllu]_`3?K,K'GL"GL„,K
Y3<78HKO‡'B&O‡L9X'iKZXL
 ~YOi3
QRAS,7F;X!'r4XvK”
!* ')7R)4304+8>
O=* RUF4Qf3?K*PVQO=“

;8UO)XOGOOH*a5>[XO8YY333
0PKF9)8nG~RP3SZ"*;AA*,
8R O=RKPQf+OLX4O=
>30!4O=Sf8K~!HXH,t
(3JRASvK9KX9)3?K OP
U!=GL"X)X'( 3D OZ+P7K
PQi*8nY=7')=S
K8KOCK(KV)*3?KK*OZ\
;7OS]ch`3
2.9.2 Bệnh tích
Q5!L"ASGOQBXm KL !
KK;,RCRXKjXRGL"]h`3
QL"AITX'
9;HKOoXRX)XNX88K"mK&
*3@=7SZ"O)XFX)*;"[TX;#LPK
8K\OGOU.
$Bc3^3MP'9
;H
$B  c3c3  D  R  A  5&  P  '
9OQL 
JAOQBS>",OS!3DRRK
 L LLKOiY*…O)OXPK83sK
aOQL ƒ4'8H=aOF !3
:RK4w9xXHH"k!T*;L XC\;
LQ3DR=L X8ORO)3
?OR!C**;8v3s vPBYXB'X
BRO>K>A3@,L8 vK=*9U
RXKCnX\*P3SZ"*U8 v8KL PQ
7>=KX>R)>G]^e`3


JUBjKL
 X!GXP=7
O!!!†rK8KX>
"[r3
$7&
$Bc3b3 Xuất huyết ở niêm mạc dạ dày tuyến
Hình 2.6.D' XL XRt
(Ppphảiphải)[29]
$Bc3z3jK*;L
 R
JW8K@wdezbx]by`L8*('8K7n'
8C* OF*•9LK,tXOU*K8;ABK
8i',7n'3J OF*•*(jLKm
'XjC\! *K88KRK8KO!"XOU*
L„,7n'X*(' XRt3:;K*(
'L K8X'*;8†*o]by`3
J•F'S*Q+X"[TXL XRt
KOF7R!8K=7F'!,7
!XGL"T7)8K7&3
DV* OF*•m)4G5!OZ
*…S3MQ8QPQLV* OFm)
4XOU*KQf3<PKZ!!8K8GPmm
)8HjC\! *K"5R5&3JA
4jTPQL,! *K)8[g7]_`3
2.10 Chẩn đoán
2.10.1 Chẩn đoán phân biệt
JDW\"C*8H!*!*,*CL
RX&o8HN'FmK8KCg 3'C
KQm ,j7R4+GL"8K!]h`3JAOU
KZL 798K8v=3JDWQ

L"A\K"C*8H!*9\!m)3
› M!8H*DWX*4KX"P4KX
*[w"x8K*&!!S4*B
S9)3DK,YPQ"!L!FRtK
3D KvPQL"! ]de`3
›{*o [K.!GPQCA9
)nX")H!SZ",PQ\KBLV
OQRtLLK!*…O)O3D Q8[
Nƒ\KBLjPUm8# Pasteurella*"#3
›J8A5&9\TP'G
L"GPZ8=8KL ROSG
L"3D Q8QROSGL"ƒBLQ*K
]h`3
›J8A5&9\!*DW,'O=)
NL"4XGP')8KP3{Kd!
FK*;8A5&9\GPL8v8KL
 OS=8KTGP')*DW
]de`.{KO‡XP&O‡'K8nGiR*BS3
si'[BX;R3{*DWBK&O‡'PQk
O‡XO‡9'X'\8† ]de`3
›JAK&*O>Q )!78H*
DWGP!LL ]h`3
+ J@Q'8K*!,!UO=X
rO)3F!*OPGP*AOS=OQ
B*DWXK8KOPK* OF7,X!X>,
*@X8KL f,* 8f9\ ]de`3
›* 88K-DRRK GL
 K*;kPX"m=H"*fO>K]h`X~\"C*
~GP'8K*AmOSP8K)
*DW]de`3

HOC*DWOfk*;K*;&K
wKNK~)w8xx]^l`3sB8>XOQ"C*
*KG"&\3D=7K' ]dy` B
*KTPV'8K*A!*3@=7OUOQ
!*
/<78H*~)BT7X&HXHTX
KACX"[9X "[O)8KXVaGPG
SA!XCL HcllyL"F* BAL"[9
KAKL"F* KKCXo8K5+XY*DWB
T7X&HXHTXXKAGXG"[
9K€CXo78K5+R3
JDWQL"ASmTX*(mP,8KRX
8[NPK&XQHL"•XUU” œPX
PœXv,OQAAXQfAUGOQBOK
P9K8K))X &!3
J~XHOC*;RX8&iROSn!X
Uv701:X*C3
2.10.2 Chẩn đoán virus học
2.10.2.1 Thí nghiệm trên gà
0PQNK8KKFO F,K3GS
[KYc/^!F3sK"&O&*&…KOZNKKG
*DW8K"Y8DW)KOQC
*3J"#OZ[OQv7LKfX"FXX!m
KH *3J"#)OZ*&5&HO!U
;zlu3J"#OZ9!8K K\;clu
8HH•3NqUC)*FdllO48;
"8K=Z4O4"a"C7\
;3<QaZ"8KmR=S!#XO\
;*"#K]ch`3@oOAC*KOQ"C>"R*j
A3lXz/d*"#aK8KHX*"

;A5&3@an*"#c/^K&o3
^/zK!'O)ƒL3_/dlKKƒ 8H
!*Am*j]ch`3
?C\*Kk\;Of ˆXz"GK
dlKF8K~GX9klXd/lXca"G(OQm
L3sDWOS"7S  *Kk^l/byS
8HjLmO!L 8KF' H3
MQH'LPZ ()K3DV*K
75!byST)Q&+ ()8BP=7
m X9)9O)8  *K3S
Z" 5&CA) "o "OSoO=8K)*K
']ch`3
2.10.2.2 Thí nghiệm trên chim
0*(C8KH\;*"#KPXm4
mK*Xh/_K*(CmTX7O=O b^
l
0X*i+Xf!X
dd/dcK8>79HX€"Ci(X*R
C8KCB( 3D ;H'P'8XB
K'y*(C€iX€"C("C8K ,K'dd/
d^3@F!LRP"mLKX79o!X
L ]^^`3
08K*";O[;H'P'8",
(O=dl
^
X8>*;~) XS PQk_/d^K3@F
!P*Ao!KCXUXA5&PL))]^z`3
2.10.2.3 Thí nghiệm trên tế bào tổ chức
sH\;*"#PQC\ *K**
*KK=7R *K=H"!38KK“=O=j

8K7Z8P*"#XQHAQ8ƒLH"
*KUK7 O(O9XLfC
*K8PRkO!3:; *K 5&4A8H"&'
 ()K]ch`3
2.10.3 Chẩn đoán huyết thanh học
2.10.3.1 Thí nghiệm trung hòa
* Trung hòa trên gà thí nghiệm:
:[GKX=GA8K=GO7'3.GA
OZ8DWXGO7'GOZ83z/_
K&GO9OZ*"#mK*DW8K
H*";O[mK3D *"#'8DWB,G
AKG*; K8n"!Q*BSX*,8B
8KOfP!Q7R8DWX*"#
8KB8DWP*"#Of*;!QKYX
GY8OQC*KOZ3OP,GO7'XK*;
 X*,8B,GKKGOZ8GP!Q7
8DWOQ*&8K]^z`3
* Trung hòa trên môi trường tế bào tổ chức, trên phôi thai gà và trên
động vật thí nghiệm:
@aO7Z'[G.GA8KGO7'3
.GA<ZUL*"#OfOZaZ"
8H=! DW4O4OQ,^_
l
0d/cS3
.GO7'0€OZ8KL*"#P8DW3
Kết quả: D *"#P '8DW B!GA
KGS *KF'X"GK8KO=8>A8n
"!Q8K7*BSX8B8P*"#Of*;! 
DWYXGY8OQCmR *KUK