1
(NMCT)
(BN) NMCT
[6
1].
.
trong ,
l(
-HATT, ), c
(
) [34], [64], [65], [38], [27], [41],
BNP
(NT-proBNP)
[18], [53], [55], [72], [22], [39], [68], [19], [24], [26], [43], [44], [61],
,
(CK, CK-MB)
?
qua da.
2
,
NT- proBNP)
qua da
2
1. CRP, NT-
qua da.
2.
qua da.
3
tim
[16], [75].
[67].
ca 8
3.662
,
n
8].
[21]:
4
vi
3. g.
NMCT
American College of C
2], [69]:
troponin)
sau:
c.
5
V
-
34],
[64].
-
[65].
6
- :
9], [52].
- HATT (< 100 mmHg):
ng HATT
ra
-Jarisch) [15].
- (> 90 chu k):
23].
-
[38]:
Killip
I
6
II
17
III
38
IV
61
- [51
74
+ Killip III, IV
7
67 kg
(%)
0
0,8
1,0
1
1,6
1,0
2
2,2
1,8
3
4,4
3,0
4
7,3
4,2
5
12,4
6,7
6
16,1
7,7
7
23,4
12,1
8
26,8
16,3
> 8
35,9
17,2
1.3.2.
-
6].
-
cho BN [10].
-
4,9%) [14].
8
-
2008):
, trong
.
-
theo
17].
1.4
1.4
1.4.1.1-MB:
-
0
C, CK-
-
-72h.
CK, CK-
s
1.4.
1.4.1.3. Lactat dehydrogenase (LDH): -
--
trong NMCT.
1.4.1.4. Myoglobin:
-
9
BIOCHEMICAL MARKERS IN AMI:
RELEASE, PEAK AND DURATION OF ELEVATION
CARDIAC MUSCLE CELL
Size and subcellular distribution of myocardial proteins determines time
course of biomarker appearance in the general circulation
10
1.4
1.4.2.1. Troponin [3]
11
[3]
--MB
-
-9
12].
12
1.4.2.2
48h.
*
chemotactic protein-1, interleukin-
VCAM-
(IL-1, IL--
13
-
- -
-
14
-B (NF-
- n, interferon, TNF-
-
-
---
-
--
CD40L-
-
metalloproteinase (MMP-
15
-1 (sICAM-1)
P-selectin
[56]
16
2.2.2.3. CRP
-
i
-
proBNP1-134
h1-108
-
-
[47], [76].
17
-
-angiotensin-
18
-
-
-
-
-proBNP
-
-
-
-
-
-
-
-
19
--
-proBNP
3.1. Troponin
3.1.
CK-
American Journal of Cardiology)
;
CK, CK-
20
CK-
-
-
,
-
-
-MB [18].
-
Clinical
Chemistry
-
-MB (r
21
-
p < 0,001).
-
Clin Res Cardiol
v
22
r
p
r
p
EF
-0,56
< 0,001
-0,70
< 0,001
ESV
0,58
< 0,001
EDV
0,55
< 0,001
23
-
-
-
-0,48, p < 0,001).
NMCT
n
:
3.1.4. Troponin trong
(6.9 ng/ml)
(p < 0.01).
-
(p <0.01).
24
Ann Clin Biochem
Troponin T
sau
Trong kh
-
-
3.2. CRP
3.2.1. CRP
25
Heart
-
--
-
--
3.2.2. CRP trong
-4